- Comp-neuro - lists.cnsorg.org

Video recording from Online Workshop "Towards multipurpose neural network models II: Model testing and model fitting"

by Zélie Tournoud

Dear colleagues, We are happy to inform you that the video recordings from the *Workshop on "Towards multipurpose neural network models II: Model testing and model fitting" *are now available to watch online: See the playlist here. <https://www.youtube.com/playlist?list=PLGAiaveljnk9yz_vMjlZckOMnObk1WtlJ> ** **It took placefrom 30 September to 01 October 2021 and has been organized by Anton Arkhipov (Allen Institute, Seattle), Gaute Einevoll (NMBU/University of Oslo), with the support of the European Institute for Theoretical Neuroscience. We hope the content for these videos will be of interest for you. Kind regards, *Zélie Tournoud*/ Communication manager at EITN/ *European Institute for Theoretical Neuroscience (EITN)* UMR 9197 – *NeuroPSI*(Institut des Neurosciences Paris-Saclay) CNRS – Université Paris-Saclay 151 route de la Rotonde Bâtiment 151 91400 Saclay https://www.eitn.org */Mailing address:/*/// UMR 9197 NeuroPSI BP 45 – 91940 Les Ulis Courtaboeuf/ **

Dec. 2, 2021

Doctoral position on foraging dynamics in natural environment.

by Ahmed El Hady

We are offering a PhD position at the International Max planck Research School for Quantitative Behavior, Ecology and Evolution from lab to field (IMPRS-QBEE) situated in the beautiful German town of Konstanz. It is a newly established highly interdisciplinary school that brings a full breadth of expertise from ecology to physics to computer science to neurobiology in order to understand animal behavior across the whole animal kingdom . For more information about the school, please check this website: https://www.ab.mpg.de/3228/imprs . The deadline for application is mid-january 2022: https://www.ab.mpg.de/406326/applications-2022 The PhD project I am offering is a joint project between my group and the group of Einat Couzin , both situated at the Center for advanced study of collective behavior and the Max Planck institute of Animal Behavior in Konstanz. Below are the details of the project ( https://www.ab.mpg.de/426580/Couzin-Fuch_El-Hady ): Foraging is a universal, evolutionary conserved, behavior as animals in nature forage in groups across large spaces looking for resources to satisfy their energetic needs. To date, laboratory experiments have been constrained to animals foraging in small spaces and in small groups. There is an increasing evidence that both neural and behavioral dynamics, however, are principally different in natural spatial scales. The project aims to investigate basic principles underlying foraging decisions in large-scale dynamic environments, that mimic natural habitats. We will focus on two very different model organisms, each exhibits different adaptations to foraging under conditions of considerable uncertainty: swarm-forming locusts and rats. The experiments will be performed at the imaging hangar in the visual computing of collective building at Konstanz University. The imaging hangar is the largest indoor animal imaging facility in the world, offering the opportunity to perform foraging experiments at an unprecedented scale. Using patch foraging as a quintessential behavioral paradigm, and a combination of high throughput continuous video tracking and quantitative modeling approaches, we aim to elucidate how foraging strategies are updated in a changing social and physical world. You will join our interdisciplinary team at the Max Planck Institute for Animal Behaviour (https://www.ab.mpg.de/) and the Excellence Cluster for the Advanced Study of Collective Behaviour (www.exc.uni-konstanz.de/collective-behaviour) The Max Planck Society and Konstanz University are equal opportunity employers that are committed to provide employment opportunities to all qualified applicants without regard to race, color, religion, age, nation, sexual orientation, gender identity, or disability. They seek to increase the number of women in those areas where they are underrepresented and therefore explicitly encourage women to apply. Requirements: • MSc in neuroscience, biology, physics and a clear interest in animal behaviour. • Quantitative skills. Proficiency in at least one programming language is required (C, Python or Matlab) • Good communication and writing skills. Supervisors: Ahmed El Hady ahady(a)ab.mpg.de Einat Couzin-Fuchs einat.couzin(a)uni-konstanz.de For more information , please do not hesitate to contact me.

Dec. 2, 2021

Diversity in Research Papers Award - applications by 21.12

by Abigail Morrison

Dear colleagues, the Human Brain Project<https://secure-web.cisco.com/1W1yXA3r1eMXG2QECkXE7pE47kLRIgETwWjcqqDDu-0Bvs…> (HBP) launched the (DIRPA), inviting applications for the Best Diversity in Research Papers, i.e. publications that consider diversity traits such as sex, gender, age, ethnicity, etc. in their specific field of research such as neuroscience, AI or robotics. Differentiating variables has been recognised to be relevant from the level of stem cells to the reproduction of biases by AI applications. Considering sex/gender has become a mandatory requirement for Horizon Europe projects<https://secure-web.cisco.com/1N4suA7zlj2Htjj6Fi7aKdpAUd4iHisVvlrhWpFIHgjDbu…> (see also “Gendered Innovations” policy report<https://secure-web.cisco.com/1Z9Dobl_iN2xA4AcAe6cJuwwKTPhmwWVtRS87wuGclvzeA…>). The most outstanding papers will 1. be awarded with a certificate of honour. 2. be presented at the heart of a webinar to a large audience in a dedicated online event organised and promoted by the HBP<https://secure-web.cisco.com/1W1yXA3r1eMXG2QECkXE7pE47kLRIgETwWjcqqDDu-0Bvs…> and EBRAINS<https://secure-web.cisco.com/18-6-i2_g4ZweyCoaJtiyysPp45EhpsYRRnqKX35IoyD3n…>, where the authors will discuss their research related to diversity with Lutz Jäncke and further keynote speakers in April 2022. 3. be promoted with a news feature on the HBP and related Web Sites, as well as social media channels with several thousand followers. 4. especially early-stage researchers will receive a voucher for a HBP event of choice. Submission deadline: 21st December 2021 More information & submission: https://www.humanbrainproject.eu/en/about/gender-equality/measures-and-mate… _______________________________________________________ -- Prof. Dr. Abigail Morrison IAS-6 / INM-6 / SimLab Neuroscience Jülich Research Center & Computer Science 3 - Software Engineering RWTH Aachen http://www.fz-juelich.de/inm/inm-6 http://www.fz-juelich.de/ias/jsc/slns http://www.se-rwth.de Office: +49 2428 8097504 Fax # : +49 2461 61-9460 Pronouns: she/her ------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------ Forschungszentrum Juelich GmbH 52425 Juelich Sitz der Gesellschaft: Juelich Eingetragen im Handelsregister des Amtsgerichts Dueren Nr. HR B 3498 Vorsitzender des Aufsichtsrats: MinDir Volker Rieke Geschaeftsfuehrung: Prof. Dr.-Ing. Wolfgang Marquardt (Vorsitzender), Karsten Beneke (stellv. Vorsitzender), Prof. Dr. Astrid Lambrecht, Prof. Dr. Frauke Melchior ------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------

Dec. 1, 2021

PhD position on electrical stimulation-induced changes in neuroplasticity at Inserm, Rennes, France

by Elif Köksal

*Title*: Neuro-inspired macroscale models of electrical stimulation-induced changes in neuroplasticity *Context*. Epilepsy refers to a neurological disorder that affects about 1% of the general population. Recent findings indicate that non-invasive brain transcranial current stimulation (tCS) is safe and of therapeutic promise in epilepsy. However, it is not yet indicated as a standard treatment due to major scientific limitations: unknown mechanisms of action, insufficient account for patient-specific factors, poor understanding of short- and long-term effects. The ambition of the GALVANI Project (ERC-SyG 2019; 2020-26) is to transform the care of a large fraction of patients living with drug-resistant epilepsies by solving a fundamental problem: to efficiently target and control large-scale epileptic brain networks with tCS-induced neuromodulatory weak electric fields ( https://www.galvani-lab.eu/) *Rationale*. Neuroplasticity refers to a wide ensemble of brain changes at cellular and network level that result from learning, practice, environmental influences, etc. In the normal brain, neuroplasticity is physiological process that allows for acquisition of new competences for instance. In the epileptic brain, neuroplasticity is a pathological process which alters the balance between excitation and inhibition giving rise to epileptic seizures. Neuroplastic changes may occur at different time scales (short and long) and may potentiate or, on the opposite, depress neuronal activity generated by brain circuits. Electrical stimulation (supra-threshold) and neuromodulation (sub-threshold) are two different methods that can be used to alter brain plasticity in order to lower hyperexcitability and subsequently decrease the occurrence of epileptiform events. *Objective*. This research focuses on neuromodulation. The objective of the proposed PhD position is to design neuroinspired macroscale models that will account for immediate (acute) and lasting (short- or long-term) effects of neuromodulatory weak electric fields, which remain elusive to some extent. *Methods*. After deep bibliographic review, biomathematical models to be developed will combine neurophysiological models of neuronal populations with mechanisms of action induced by weak electric fields on neuronal assemblies, typically on synaptic connectivity and firing rates. They will provide a unique framework to clarify and optimize the effects of dynamic E-fields induced by stimulation. They will be based on already-existing macroscale computational models which allow for simulation of epileptic activity (interictal spikes, ictal activity) generated by large-scale networks, as observed in human epilepsies. An issue to be solved is the translation from stimulation-induced short- and long-term effects at cellular level into average effects at population level. Optimization methods will be developed for identifying “therapeutic” neuromodulation parameters. Models will use the Neural Mass Model formalism (NMMs). They will be developed in Python. They will extend already-existing models at neural mass level. Strong background is available ( https://perso.univ-rennes1.fr/fabrice.wendling/) *Scientific domains*. Engineering (computational, biomedical); Physics (biophysics, electromagnetism); Biology (neuroscience); Medicine (neurology); Computer Science (computing in maths, engineering and Medicine) Scientific environment. GALVANI involves three partners: LTSI-Inserm (Rennes), AMU-APHM (Marseille) and Neuroelectrics (Barcelona). It is intended to develop the next generation of brain stimulation solutions. GALVANI can be viewed as a distributed lab (Rennes-Barcelona-Marseille) working under a common policy to ensure coherence of research and intense collaboration and cross-fertilization. Fellows will be co-supervised in a unique, shared environment with exposure to science, technology and clinical experience. *Candidate profile*. The research project is at the interface between biomathematics (neuro-inspired models), biophysics (electric field models), and neuroscience/neurology (epilepsy). The candidate will preferably have some background in dynamical systems, computational neuroscience/systems biology or in electrical engineering with experience in bio-signal processing and in biophysics. Knowledge in electrophysiology and/or EEG analysis would be an asset. The PhD fellow will join a multidisciplinary team including research scientists in biomedical engineering, neurophysiological modeling, bio-physics, signal processing, electrophysiology, neurology. *Contract*. The position will be opened* Feb. 1st, 2022*. The contract is for 3 years with possible extension (3 months). The salary will be defined according to Inserm rules regarding doctoral student remuneration. Location in the city of Rennes, France. LTSI-Inserm laboratory, University of Rennes. In addition, the PhD fellow will have the opportunity to perform visits and to actively collaborate with engineers, researchers and clinicians of the Marseille & Barcelona groups. *Contact *(please provide resume and cover letter) Fabrice Wendling (DR Inserm, LTSI, France) Email: fabrice.wendling(a)inserm.fr Pascal Benquet (Professeur, LTSI, France) Email: pascal.benquet(a)univ-rennes1.fr Elif Koksal-Ersoz (Post-doc fellow, LTSI, France) Email: elif.koksal-ersoz(a)inserm.fr

Dec. 1, 2021

Postdoc / Junior Scientist positions in Prague, Czech Republic

by Magda Pokorna

**1. Postdoctoral / Junior Scientist position in complex networks and information theory** is available to join the Complex Networks and Brain Dynamics group <http://cobra.cs.cas.cz/> for the project: “Network modelling of complex systems: from correlation graphs to information hypergraphs“ funded by the Czech Science Foundation. More information and application at https://www.cs.cas.cz/job-offer/postdoc-junior-position-Hlinka5-2021/en** 2. Postdoctoral / Junior Scientist position in Multimodal Neuroimaging Machine Learning** is available to join the Complex Networks and Brain Dynamics group <http://cobra.cs.cas.cz/> for the project: “Predicting functional outcome in schizophrenia from multimodal neuroimaging and clinical data“ funded by the Czech Health Research Council. More information and application at https://www.cs.cas.cz/job-offer/postdoc-junior-position-Hlinka6-2021/en ** ****** Do not hesitate to contact the principal investigator for informal inquiries concerning the position: Ing. Mgr. Jaroslav Hlinka, Ph.D., hlinka(a)cs.cas.cz. Jaroslav Hlinka Head of the Department of Complex Systems Institute of Computer Science Czech Academy of Sciences Pod Vodarenskou vezi 2 Prague 8, 182 07, Czech Republic Web: http://cs.cas.cz/hlinka

Dec. 1, 2021

3rd BCI-UC: Submission closes on Friday, December 3rd

by Philipp Raggam

Dear Colleagues, The *abstract submission* for the 3rd Brain-Computer Interface Un-Conference (BCI-UC) *closes on Friday, December 3rd*, *at 11:59 pm (CET)* and the *voting period on submitted abstracts begins on Monday, December 6th* [1]. Abstract submissions are text-only. The length and format of the submissions are up to the authors - use whatever format you consider best for attracting up-votes! Important dates: - *Submission deadline: *December 3rd, 2021 at 11:59 pm (CET) - *Voting period:* December 6th, 2021 - December 12th, 2021 at 11:59 pm (CET) - *BCI-UC event:* January 27th, 2022, from 03:00 pm to 09:00 pm (CET) We will invite the *authors of the top-voted abstracts to present* at the un-conference. The 3rd BCI-UC will feature *keynotes* by *Cynthia Chestek* (University of Michigan) [2] and *Thorsten Zander* (TU Brandenburg) [3]. BCI-UC is an online un-conference that provides rapid dissemination of novel research results in the BCI community. Participants can *submit abstracts* to apply for *20 minutes presentation* slots. Abstracts are not reviewed by a program committee. Rather, all registered participants can vote on which of the submitted abstracts they would like to see presented at the un-conference. Because the BCI-UC does not publish conference proceedings, submitted abstracts can report novel as well as already published work. *Registration and attendance are free of charge*. Presentations of the 1st and 2nd BCI-UC can be re-watched at [4] and [5]. *All presentations will be streamed via Crowdcast* [6] and can be accessed free of charge. Join us in supporting this novel community-driven dissemination of research results! The BCI-UC committee: Moritz Grosse-Wentrup Anja Meunier Philipp Raggam Jiachen Xu Links: [1] https://bciunconference.univie.ac.at/3rd-bci-uc/ [2] https://scholar.google.com/citations?user=36sxAZEAAAAJ&hl=de [3] https://scholar.google.com/citations?hl=en&user=0E49HxYAAAAJ [4] https://bciunconference.univie.ac.at/past-events/1st-bci-uc/ [5] https://bciunconference.univie.ac.at/past-events/2nd-bci-uc/ [6] https://www.crowdcast.io/ -- DI Philipp Raggam, BSc Research Group Neuroinformatics Faculty of Computer Science University of Vienna Hörlgasse 6, A-1090 Wien, Austria

Nov. 30, 2021

Support open neuroscience this Giving Tuesday

by Heather Topple

[image: Giving Tuesday.png] Support INCF’s mission to push global neuroscience further and faster Scientific progress is critical for providing our global community with cures and treatments for illnesses that cause pain and disability in so many lives. Neurological diseases are the leading cause of disability and the second leading cause of death worldwide, and mental health issues are increasing every year. While neuroscience has made significant progress in the last couple of decades, there is still much to do. A major barrier is that neuroscience is time-consuming and expensive. One way to remedy this is through the reuse and pooling of data and sharing of tools, which speeds discovery and increases sensitivity to the subtleties of brain function and disease. INCF facilitates this process by endorsing practical approaches and solutions for the application of open, FAIR, and citable neuroscience, and ensures impact through advocacy and efforts in training the next generation of neuroscientists in FAIR research management approaches. You can support our efforts by making a direct donation, or by sponsoring a membership for a student or colleague. Your gift will enable us to support open science for the global neuroscience community! *DONATE <https://incf.org/donate>* [image: GivingTuesday logo.png] ---------------------------- Heather Topple, BSc *Project Assistant* *Development and Communications* International Neuroinformatics Coordinating Facility Secretariat Karolinska Institutet. Nobels väg 15A, SE-171 77 Stockholm. Sweden <https://www.google.com/maps/search/Nobels+v%C3%A4g+15A,+SE-171+77+Stockholm…> Email: heather(a)incf.org Phone: +46 085 248 70 65 incf.org neuroinformatics.incf.org

Nov. 30, 2021

Apply Now: Shanahan Foundation Fellowship at the Allen/UW at the Interface of Data and Neuroscience

by Adrienne L Fairhall

***Please forward** particularly to data scientists with a Ph.D. in quantitative fields such as computer science, statistics, electrical engineering, physics, mathematics* Shanahan Foundation Fellowship at the Interface of Data and Neuroscience Overview The *Shanahan Foundation Fellowship at the Interface of Data and Neuroscience* is a three-year fellowship program that aims to: · Integrate data scientists in neuroscience research · Challenge traditional approaches to neuroscience · Provide multidisciplinary, multi-organizational co-mentorship · Provide a network and community · Support career development in data science The fellowship is co-hosted by the Allen Institute and the University of Washington (through the eScience Institute and the Computational Neuroscience Center) and is directed by Dr. Christof Koch at the Allen Institute. *Neuroscience needs data scientists.* The brain represents one of the most complex challenges facing science today. And now with advances in our methods to study the brain—Neuropixel probes that can record from 1000 neurons at once, growing consensus on data standards across laboratories—the field is flooded with data that needs interpretation. The skills of data scientists are essential to springboard the field to the next stage of discoveries. Towards that end, the Shanahan Foundation Fellowship was created to bring fresh perspectives into the field, encouraging data scientists from outside neuroscience to come and work with leading investigators at the Allen Institute and UW. The Allen Institute is unique in its infrastructure and pipeline that enables the production of standardized, reproducible data on the brain (as evidenced by our vast *data banks* <http://www.brain-map.org/>*)*. Together with our collaborators at the UW computational Neuroscience Center and eScience Institute, we provide data scientists with the ideal opportunity and resources to mine for novel insights and discoveries. Details *You do not need experience in neuroscience to apply. *The goal of the fellowship is to provide opportunities to non-traditional applicants who would not typically be funded by the typical postdoctoral fellowships in neuroscience. The fellowship has been purposefully designed to give fellows the time and mentorship to get up to speed in a new field and new data collection techniques and methods*.* Fellows will be employed by the Allen Institute as either a Scientist I or a Scientist II (with a matching salary) and will receive an affiliate postdoctoral appointment at UW. During the three-year fellowship, fellows will identify a mentor at the Allen Institute, where the fellows will be based. Fellows will select a co-mentor at the University of Washington who will provide additional guidance on a project designed by the fellow, focused on quantitative analysis of neuroscience data available through the Allen Institute’s vast data banks <http://www.brain-map.org/> – ranging from molecular, genomic, transcriptional, physiological, morphological, anatomical and functional whole-brain level in the brains of mice, non-human primates and humans – or through ongoing laboratory work. Each fellow will have the opportunity to mentor a fully-funded UW undergraduate or postbaccalaureate research assistant who helps with their research for 3-12 months. Fellows will participate in the postdoctoral career development program at the University’s *e-Science Institute* and the *UW Computational Neuroscience Center*. The eSciences Institute offers regular workshops on key topics including cloud computing, python and reproducibility. New fellows will attend the annual Summer Workshop on the Dynamic Brain <https://alleninstitute.org/what-we-do/brain-science/events-training/summer-…> where they will learn how to apply data science skills to neuroscience data and questions. Throughout the three years, fellows will be supported in developing a network in the neuroscience field and sharing their progress with peers at conferences. Up to three fellows will be selected to begin in Fall 2022. Eligibility Requirements Applicants must be data scientists in a broad sense, with a Ph.D. in a quantitative field such as computer science, statistics, electrical engineering, physics, mathematics or biology with a background in statistical, computational and machine learning methods. Ph.D.’s should have been awarded in the last 3 years. One goal of the fellowship is to build a network of collaborators, as such, priority will be given to applicants who are not currently postdoctoral fellows or scientists at the University of Washington or the Allen Institute. We believe high-quality science can only be produced when it includes different perspectives. We are building an environment of diversity and inclusion and encourage people from all backgrounds to apply for this fellowship. Application Instructions For full consideration, please submit your application by February 1, 2022. Applications may continue to be considered after this deadline on a rolling basis until positions are filled. Learn more and apply on the Shanahan Fellowship Website <https://alleninstitute.org/what-we-do/brain-science/careers/shanahan-founda…> . Applications must include: · A curriculum vitae from the applicant · Two letters of support from advisors and other mentors · A one-page personal statement from the applicant describing their history, activities, and interests as an individual (especially those outside of science) which may give the committee a greater sense of you as a person and your ability to simultaneously interact with and challenge traditional scientific fields. · A two- to three-page research statement from the applicant describing their prior research, interests in applying data science to the field of neuroscience, potential research interests (including tools they are familiar with) and how this fellowship aligns with their career goals. · The choice of the final advisor/co-advisor will be accomplished during the first year of this fellowship. Questions? Email: shanahan.fellow(a)alleninstitute.org -- Sarah A. Stone, PhD Executive Director | eScience Institute Campus Box 351570 University of Washington Seattle, WA 98195 _______________________________________________ Escience_bbl mailing list Escience_bbl(a)u.washington.edu http://mailman12.u.washington.edu/mailman/listinfo/escience_bbl

Nov. 29, 2021

Software Engineer position for International Brain Laboratory

by Hannah M Bayer

The International Brain Laboratory SOFTWARE ENGINEER <https://academic.careers.columbia.edu/#/85586> will work closely with our scientists to develop and deploy software and electronic hardware for experiment control, collection, storage, and data analysis. The experiments make use of complex control systems including video, audio, and fluidics, the data are processed by sophisticated algorithms including GPU-based deep networks, and then transferred automatically to a central database. The successful candidate will interface with scientists in our member laboratories (located in London, Lisbon, Geneva, Paris, New York City, Long Island, Princeton, San Francisco, and Ashburn VA) and with the core software development team based in Lisbon, to support experiments and ensure data is of high quality. The ideal candidate would have extensive experience with Linux, Python, Arduino systems, electronics, team programming, quality assurance, web design, and system administration. A flexible attitude, the ability to quickly adapt to new situations and learn new systems, and to work independently as part of a geographically distributed team, are essential. Experience with scientific research, networking, parallel computing, or relational databases would also be desirable. As this is a distributed collaboration, the candidate should be prepared to travel to all partner sites, with a home base in Lisbon, London or New York. RESPONSIBILITIES: - To develop and support software and hardware to collect and analyse neurophysiology recordings at worldwide partner sites - To help apply these algorithms to petabyte-scale data, to draw scientific conclusions about brain function. - To support the use of the resulting algorithms and software by laboratory members and by the worldwide scientific community. - To write online documentation and help author scientific publications describing the algorithms and discoveries made with them. Any questions prior to applying, please contact info(a)internationalbrainlab.org To apply: https://academic.careers.columbia.edu/#/85586 -- Hannah M. Bayer, PhD Executive Director International Brain Laboratory

Nov. 29, 2021

SCGB Virtual Postdoc/Student Meeting: Wednesday, December 1 by Olivia Gozel

by Laura Long

The Simons Collaboration on the Global Brain (SCGB) hosts postdoc/student meetings to bring together trainees interested in neural coding and dynamics to discuss ideas and data. In addition to regional meetings in New York, Boston, and the Bay Area, SCGB holds a virtual series to connect systems and computational neuroscientists independent of geography. We would love to see you at our next meeting! Please see event details and the Zoom link below. SCGB Virtual Postdoc/Student Meeting: https://www.eventbrite.com/e/scgb-global-postdocstudent-meeting-tickets-209… Wednesday, December 1st, 12pm Eastern Time https://simonsfoundation.zoom.us/j/94767192583?pwd=TXBKNXJQYzdGTmRUZTFlUUYz… Passcode: 429535 *Olivia Gozel* Postdoctoral Researcher, Doiron Laboratory The University of Chicago *Between-area communication through the lens of within-area neuronal dynamics* Neuronal dynamics range from asynchronous spiking to richly patterned spatio-temporal activity and are modulated by external and internal sources. Numerous experimental datasets show that the shared variability can be well described by a small number of latent variables, indicating coordinated trial-to-trial fluctuations within the population. Besides, cortical areas are connected through long-range excitatory projections, and it has been shown that there exists a communication subspace between connected but distinct brain areas that predicts spiking activity in a downstream area using upstream activity. However, little is known about the effect of neuronal dynamics on interactions between brain areas. Using a layered spiking network with within- and between-layer spatially structured connectivity, we show that pattern formation decreases within-area dimensionality similarly when spatio-temporal patterns emerge within a population or when they are inherited from a connected population. Yet, the fidelity of communication from an upstream to a downstream area, as estimated by a linear reduced-rank regression measure, is affected by the origin of pattern formation. Specifically, downstream activity is poorly predicted by upstream activity when spatio-temporal patterns emerge downstream, while it is particularly well predicted when shared fluctuations are mostly inherited from the upstream area. Interestingly, examination of spiking activity reveals that, even in the scenario with apparent disrupted communication, the downstream area is effectively driven by upstream activity, as expected from the strong feedforward connection strengths between layers. A mismatch in within-area dimensionality between upstream and downstream areas appears to underlie the seemingly weak communication. These results expose the limitations of linear measures when analyzing the flow of information in brain circuits with diverse neuronal dynamics. *Please note that this meeting is open to all neuroscience postdocs and PhD students, regardless of location or SCGB affiliation (sorry, no PIs). *After Q&A with the speaker, we will open breakout rooms for anyone interested in staying to chat, network, or further discuss the talk. In addition to these breakouts, SCGB Scientific Staff will be available for "office hours" to chat and answer questions about SCGB programs and support. Registration on EventBrite is encouraged but not required: https://www.eventbrite.com/e/scgb-global-postdocstudent-meeting-tickets-209… Please contact Laura Long at llong(a)simonsfoundation.org with any questions.

Nov. 29, 2021