December 2020 - Comp-neuro - lists.cnsorg.org

Postdoctoral fellow – Systems Neuroscience of Alzheimer’s Disease

by Williamson, Ross S

Dear all, Apologies for the cross-posting. A postdoctoral position is available in the Williamson and Thathiah laboratories at the University of Pittsburgh School of Medicine to investigate the links between hearing loss and the pathophysiology of Alzheimer’s disease (AD). The information from our senses is used throughout everyday life to guide the decisions we make and the actions that we take. For example, the sound of sirens when driving leads to a decision regarding an appropriate motor action (whether or not, and where, to pull over). The neural circuits that underlie these cognitive processes (accumulation of sensory evidence, short-term memory, perception decision-making, etc.) can be severely altered by disease. Hearing loss is prevalent in >40% of individuals older than 60 years and is considered to be the most heavily contributing modifiable risk factor to dementia. It is our hope that by identifying and studying the neural circuits involved, we will provide insight to drive subsequent therapeutic intervention strategies that may lead to the repair (or prevention) of damage. The Williamson Laboratory uses a variety of state-of-the-art tools to probe the neural circuits of awake mice, including two-photon calcium imaging and high-channel count electrophysiology (both with single-cell optogenetic perturbations), head-fixed virtual reality behaviors, and statistical approaches for neural characterization. A significant focus of the lab is to understand how sensory information is used to guide purposeful behavior in models of health and disease. Details on the research focus and approaches of the Williamson laboratory can be found here: https://www.williamsonlaboratory.com/research/ The Thathiah Laboratory uses molecular, cellular, and behavioral approaches along with optogenetic tools to investigate the mechanisms of AD pathogenesis. Recently, the Thathiah lab teamed up with the Williamson lab to investigate the putative causal relationship between hearing loss, disease pathogenesis, and cognitive impairment using our complementary research approaches in AD mouse models. Details on the research focus of the Thathiah laboratory can be found here: https://www.neurobio.pitt.edu/people/amantha-thathiah Both laboratories are embedded within the Departments of Neurobiology and Otolaryngology, are members of the University of Pittsburgh Brain Institute, the Pittsburgh Hearing Research Center, and are affiliated with the Center for Neuroscience (CNUP) and the Center for the Neural Basis of Cognition (CNBC). The Thathiah laboratory is a member of the Pittsburgh Institute for Neurodegenerative Diseases (PIND), the Alzheimer’s Disease Research Center (ADRC), and the Aging Institute. Postdoctoral fellows will be part of a highly supportive and diverse research environment with excellent career development opportunities. The University of Pittsburgh was ranked third in terms of total NIH funding received in 2018. The Global Livability Index (The Economist) recently ranked Pittsburgh as the second most livable city in America. The University of Pittsburgh School of Medicine is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, creed, sex, sexual orientation, gender identity, national origin, ancestry, age, veteran status, disability unrelated to job requirements, genetic information, military service, or other protected status. Requirements: Applicants must have a Ph.D. in Neuroscience or a relevant field and must be eligible for employment in the US. We are looking for individuals with an excellent record of research achievements and expertise at the intersection of two or more of the following areas: electrophysiology, two-photon imaging, quantitative behavior, and computational neuroscience. Experience with molecular and biochemical techniques is preferred but not required. Excellent verbal and written communication skills, technical expertise, and scientific creativity are essential. Applications will continue until the position is filled. Contact: Interested candidates should send a brief statement of research interests, a current CV, and the names and contact information of three references to: Dr. Ross Williamson: rsw(a)pitt.edu<mailto:rsw@pitt.edu> Dr. Amantha Thathiah: amantha(a)pitt.edu<mailto:amantha@pitt.edu> Thanks, Ross ---------------------------------------------------------------------------------------------------------- Ross S. Williamson, Ph.D. | Assistant Professor | Otolaryngology, Neurobiology Pittsburgh Hearing Research Center | Center for the Neural Basis of Cognition University of Pittsburgh | Biomedical Science Tower | W1448 www.williamsonlaboratory.com<http://www.williamsonlaboratory.com>

Dec. 29, 2020

Postdoc at International Centre for Translational Eye Research

by Andrzej Foik

Dear all, I would like to repost our announcement about the postdoc we are looking for. we are looking for a postdoc in the neuroinformatics or bioinformatics area. Please, spread the word to your friends if you can. The Ophthalmic Biology Group searches for candidates with a Ph.D. degree experienced in computational biology techniques such as neuronal network modeling, electrophysiological data analyses and/or bioinformatics, and DNA/protein modeling. Candidates should be interested in translational research and the development of new therapies to cure blindness or other diseases. The postdoctoral scholar will have a direct impact on lab development and its success in publishing in high impact factor journals. The person will be also responsible for performing dynamic research to create a competitive research group. The position will be assigned to the Ophthalmic Biology Group led by Andrzej Foik Ph.D. focusing on the development of new viral therapies, visual information processing in the visual system before and after plasticity that happens due to vision recovery or disease. https://euraxess.ec.europa.eu/jobs/580785 https://ichf.edu.pl/en/job/international-centre-for-translational-eye-resea… Best regards, Andrzej Foik -- Andrzej Foik, PhD Group Leader Ophthalmic Biology Group International Centre for Translational Eye Research (ICTER) Institute of Physical Chemistry PAS ul. Kasprzaka 44/52, 01-224 Warszawa mobile: +48 695 497 065 office: +48 22 343 3204 email: afoik(a)ichf.edu.pl; andrzejfoik(a)gmail.com NIP: 525-000-87-55 www.icter.pl The controller of your personal data is the Institute of Physical Chemistry of the Polish Academy of Sciences with its registered office in Warsaw, NIP: 5250008755 (the "Institute"). The Institute will process your data for the purpose of carrying out scientific and research activities, providing services and contact with the Institute, on the basis of a contract (in connection with the performance of the contract or in order to take action on your request before the contract is concluded – Article 6, paragraph 1, letter b) of GDPR), the legitimate interest of the Institute (Article 6, paragraph 1, letter f) of the GDPR) and legal provisions (Article 6, paragraph 1, letter c) of the GDPR) - depending on the circumstances. You have the right to request access to your data, receive a copy of it; rectify (correct) it; delete it; limit its processing; transfer it; lodge a complaint to the supervisory body; withdraw your consent for processing at any time (withdrawal of consent does not affect the lawfulness of the processing carried out prior to its withdrawal) or to lodge an objection to data processing. More information is available on the Institute's website. http://ichf.edu.pl/gen_inf/gen_en/GDPR%20-%20General%20Information%20Clause… -- Andrzej Foik, PhD Group Leader Ophthalmic Biology Group International Centre for Translational Eye Research (ICTER) Institute of Physical Chemistry PAS ul. Kasprzaka 44/52, 01-224 Warszawa mobile: +48 695 497 065 office: +48 22 343 3204 email: afoik(a)ichf.edu.pl; andrzejfoik(a)gmail.com NIP: 525-000-87-55 www.icter.pl The controller of your personal data is the Institute of Physical Chemistry of the Polish Academy of Sciences with its registered office in Warsaw, NIP: 5250008755 (the "Institute"). The Institute will process your data for the purpose of carrying out scientific and research activities, providing services and contact with the Institute, on the basis of a contract (in connection with the performance of the contract or in order to take action on your request before the contract is concluded – Article 6, paragraph 1, letter b) of GDPR), the legitimate interest of the Institute (Article 6, paragraph 1, letter f) of the GDPR) and legal provisions (Article 6, paragraph 1, letter c) of the GDPR) - depending on the circumstances. You have the right to request access to your data, receive a copy of it; rectify (correct) it; delete it; limit its processing; transfer it; lodge a complaint to the supervisory body; withdraw your consent for processing at any time (withdrawal of consent does not affect the lawfulness of the processing carried out prior to its withdrawal) or to lodge an objection to data processing. More information is available on the Institute's website. http://ichf.edu.pl/gen_inf/gen_en/GDPR%20-%20General%20Information%20Clause…

Dec. 28, 2020

New Journal: Mathematical Neuroscience and Applications

by Zachary Kilpatrick

We are pleased to announce the creation of "Mathematical Neuroscience and Applications". The aim of this new journal is to publish the best work in mathematical neuroscience and its applications and making it broadly available to the scientific community in a completely open fashion, i.e. at no costs for readers and authors (no APCs). The webpage of the journal can be found at https://mna.episciences.org/ <https://secure-web.cisco.com/1Th57tM0Q4wnQK5WU9a83gEk5eiepY75pxIXyIVdMZmATN…> where more information such as how to submit an article, or the list of Editorial Board Members, https://mna.episciences.org/review/staff <https://secure-web.cisco.com/1CXJhkD3WpGFVRfTHEqp6vfR8XHQDkEeIIbSjzi2e5bXzh…> , is available. This is the Diamond Open Access model which is made possible in our case thanks to the support of Episciences, https://www.episciences.org/# <https://secure-web.cisco.com/1EwusptV_q2y1ZQTKNt9O1K0__jJocYNjvm6c6ar0ARXwJ…> Editorial Board Members of MNA are looking forward to publishing your work. Feel free to reach out to us with any questions. Olivier Faugeras (Editor in Chief), Inria, France Peter Ashwin, University of Exeter, UK Paul Bressloff, University of Utah, USA Stephen Coombes, University of Nottingham, UK Carina Curto, Pennsylvania State University, USA Susanne Ditlevsen, University of Copenhagen, Denmark Antonio Galves, University of São Paulo, Brasil Zachary Kilpatrick, University of Colorado Boulder, USA Carlo Laing, Massey University, Auckland, New Zealand Eva Löcherbach, Paris I University, France Andre Longtin, University of Ottawa, Canada Benoit Perthame, Sorbonne University, France Patricia Reynaud-Bouret, Côte d'Azur University, France Andrey Shilnikov, Georgia State University, USA Wilhelm Stannat, Technische Universität, Berlin, Germany Etienne Tanré, Inria, France Michèle Thieullen, Sorbonne University, France Stephan A Van Gils, Universiteit Twente, Netherlands Romain Veltz, Inria, France Martin Wechselberger, University of Sydney, Australia

Dec. 27, 2020

ANDA 2021 - G-Node Advanced Neural Data Analysis Course, April 19-29, 2021

by Thomas Wachtler

ANDA 2021 - G-Node Advanced Neural Data Analysis Course April 19 - 29, 2021 _Due to the Covid-19 pandemic, this 4th ANDA course will be held as an online course_ Techniques to record neuronal data from populations of neurons are rapidly improving. Simultaneous recordings from hundreds of channels are possible while animals perform complex behavioral tasks. Analysis of such massive and complex data becomes increasingly challenging. This advanced course aims at providing training in state-of-the-art analysis approaches in systems neuroscience. The course is addressed to excellent master and PhD students and young researchers who are interested in learning advanced techniques in data analytics and in getting hands-on experience in the analysis of electrophysiological data. Internationally renowned researchers will give lectures on statistical data analysis and data mining methods with accompanying exercises. Students will define and perform their own analyses on provided data to solve a challenge. Participants are required to have a strong interest in data analysis, a background in a mathematical or related field, knowledge of algebra, matrix operations, and statistics, and need to have solid programming experience (preferably in Python). Faculty · Michael Denker, Jülich Research Center, Germany · Udo Ernst, Univ. Bremen, Germany · Sonja Grün, Jülich Research Center, Germany · Björn Kampa, RWTH Aachen Univ., Germany · Adam Kohn, Albert Einstein College of Medicine, New York, USA · Jakob Macke, TU Munich, Germany · Luca Mazzucato, Univ. of Oregon, Eugene, USA · Martin Nawrot, Univ. of Cologne, Germany · Yifat Prut, Hebrew Univ. Jerusalem, Israel · Hansjörg Scherberger, German Primate Center, Göttingen, Germany · Thomas Wachtler, LMU Munich, Germany Topics covered Single neuron properties and statistics · Stochastic processes · Surrogate methods · Detection of spatio-temporal patterns · Unitary Events · Statistical analysis of massively parallel spike data · Higher-order correlation analyses · Elephant toolbox · Spike-LFP relationship · Population coding · State space analysis · Machine learning · Data mining · Research data management and reproducibility Application deadline: January 31, 2021 For further information see http://www.g-node.org/anda

Dec. 23, 2020

Announcing the 2nd Brain-Computer Interface Un-Conference (2nd BCI-UC)

by Moritz Grosse-Wentrup

We cordially invite you to the 2nd BCI Un-Conference (BCI-UC) on February 10 and 11, 2021, from 03:00 pm to 08:00 pm (CET)! https://bciunconference.univie.ac.at/2nd-bci-uc/ The BCI-UC is an online un-conference that provides rapid dissemination of novel research results in the BCI community. The BCI-UC does not publish conference proceedings. As such, submitted abstracts can report novel as well as already published work. The BCI-UC does not have a program committee that reviews submitted abstracts. Instead, all registered participants can vote which of the submitted abstracts they would like to see presented at the un-conference. Registration and attendance are free-of-charge. The second BCI-UC will feature keynotes by Marco Congedo [3] on Riemannian transfer learning and by Camille Jeunet on user-centered BCI design [4]. All presentations of the first BCI-UC, which >300 participants attended, can be re-watched at [2]. Registration and abstract submission are open as of today [1]. Voting on submitted abstracts begins on January 13th. Abstract submission remains open until January 25th, 11:59 pm (CET). The voting phase ends on January 27th, 11:59 pm (CET). We will invite the authors of the top-voted abstracts to present their work at the un-conference. For the 2nd BCI-UC, we solicit two types of submissions: * _Presentations_ are applications for 20 minutes slots by a single presenter. * _Mini-symposia_ are applications for 60 minutes slots by multiple presenters on a coherent topic, possibly including a panel discussion. Submissions are text-only. The length and format of the submissions are up to the authors -- use whatever format you consider best for attracting up-votes! Voting procedures will not distinguish between the two submission types, i.e., the community decides on the fraction of presentations vs. mini-symposia. Join us in supporting this novel community-driven dissemination of research results! The BCI-UC committee: Moritz Grosse-Wentrup Anja Meunier Philipp Raggam Jiachen Xu Links: 1. https://bciunconference.univie.ac.at/register-vote/ 2. https://bciunconference.univie.ac.at/1st-bci-uc/ 3. https://sites.google.com/site/marcocongedo 4. https://camillejeunet.wordpress.com/ -- Univ.-Prof. Dr.-Ing. Moritz Grosse-Wentrup Research Group Neuroinformatics Faculty of Computer Science University of Vienna Hörlgasse 6, A-1090 Wien, Austria moritz.grosse-wentrup(a)univie.ac.at +43-1-4277-79610 http://neural.engineering/

Dec. 23, 2020

Open Position at Goettingen University - Postdoctoral Researcher (f/m/d) - SPP 2205

by von Behren, Christina

Dear list, We would like to draw your attention to the postdoc opportunity below: The Department of Data-driven Analysis of Biological Networks at the Georg-August-Universität Göttingen invites applications for a position as Postdoctoral Researcher (f/m/d) This position is available starting from March 1st, 2021. It is a full time position with a limited contract of 3 years with the possibility of an extension for one additional year. Salary and working hours will be according to the German grade 13 TV-L (100 %, currently 39,80 hours per week). The position will be associated with the group of Prof. Michael Wibral. We are recruiting a Postdoc for the interdisciplinary research project "Evolutionary Convergence of Hierarchical Information Processing" funded by the German Research Foundation (DFG) within the research initiative SPP2205 "Evolutionary optimization of neuronal processing". The project aims to establish the common information theoretic principles of computation in hierarchical neural systems that are conserved across species from drosophila, via rodents to primates and humans. We are looking for candidates with an excellent PhD in neuroscience, cognitive science, physics, computer science or a related field who are committed to pursuing a career in research. The successful applicant will develop and apply novel information theoretic measures to electrophysiological neural recordings and calcium imaging signals to investigate signatures of predictive hierarchical information processing. The ideal candidate should have excellent skills in scientific writing, experience with the application of information theory to biological data, and should have demonstrated her/his ability to work independently. Prior experience with predictive coding theory and experiments are plus. Proven coding skills in a language relevant to data analysis (e.g. Python, Julia, R, Scala, Java), prior experience with research-data management systems (RDMS) are also considered as an advantage. We expect the job holder to establish a local database that organizes the vast amount of research data in this project. We offer the opportunity to become a member of a vibrant community dedicated to innovative research and teaching at the frontier of the exact and biological sciences, and to connect to the latest developments in information theory, including partial information decompositions. The Göttingen Campus is a leading center of biophysics and neuroscience in Europe hosting numerous internationally renowned research institutions, including the University and its Medical Center, the three life science Max Planck Institutes, the European Neuroscience Institute, the German Primate Center, and the Bernstein Center for Computational Neuroscience (BCCN) Göttingen. The University of Göttingen is an equal opportunities employer and places particular emphasis on fostering career opportunities for women. Qualified women are therefore strongly encouraged to apply in fields in which they are underrepresented. The university has committed itself to being a family-friendly institution and supports their employees in balancing work and family life. The mission of the University is to employ a greater number of severely disabled persons. Applications from severely disabled persons with equivalent qualifications will be given preference. Please submit your application in digital form only and send all relevant documents in one single PDF-document, including a letter of interest, your curriculum vitae with a list of publications, copies of your certificates and contact information of at least two references to christina.vonbehren(a)uni-goettingen.de<mailto:christina.vonbehren@uni-goettingen.de> by January 15th, 2021. If you have any questions, please contact Prof. Dr. Michael Wibral, via e-mail: michael.wibral(a)uni-goettingen.de<mailto:michael.wibral@uni-goettingen.de>. Please note: With submission of your application, you accept the processing of your applicant data in terms of data-protection law. Further information on the legal basis and data usage is provided in the Information General Data Protection Regulation (GDPR)<https://www.uni-goettingen.de/de/document/download/e0b7459b97d917e68e3464b8…> ------ Campus Institute for Dynamics of Biological Networks Bernstein Centre for Computational Neuroscience Goettingen University of Goettingen Postal address: Max Planck Institute of Experimental Medicine Hermann-Rein-Str. 3 37075 Goettingen Germany

Dec. 22, 2020

Scientist position in modeling at the Allen Institute

by Anton Arkhipov

Join us to analyze world-class experimental data and build the next generation of brain models! This opening is in the lab of Anton Arkhipov at the Allen Institute (Seattle, WA). One position is already taken, but one is still available: Scientist I - Bio-realistic Modeling of Reconstructed Cortical Tissue See details and apply here: https://alleninstitute.hrmdirect.com/employment/job-opening.php?req=1415274 The Scientist will focus on data analysis and modeling of structure, activity, and computations in mouse cortical circuits. This project will take advantage of unprecedented experimental datasets from the Allen Institute that contain a systematic characterization of synaptic connections between the cell types (https://portal.brain-map.org/explore/connectivity/synaptic-physiology) and a connectome of individual neurons coupled with dense recordings of activity in the mouse visual cortex (https://microns-explorer.org<https://microns-explorer.org/>). The Scientist will work collaboratively with colleagues to integrate these data into new, highly realistic network models of cortical circuits, use the models to explore theoretical predictions, and provide them as a resource to fuel future theoretical, modeling, and experimental work in the community.

Dec. 22, 2020

[JOB] Postdoctoral Fellow in Concussion Neuroscience, Machine learning and Cloud Computing

by Franco Pestilli

We would appreciate if you could share the ad below to relevant list. Drs. Nicholas Port and Franco Pestilli are seeking a Postdoctoral Fellow or Research Associate to join a multi-institutional team of Neuroscientists, Computer Scientists, and Engineers to work on a unique project to apply Machine learning and Cloud computing to improve our understanding of concussion and mild Traumatic Brain Injury. Applicants are invited to apply for this research Postdoctoral Fellow or Research Associate, non-tenure track position with a proposed start date of summer/fall 2021. The primary goal of the project is to use brainlife.io, and advanced machine learning methods to analyze behavioral and clinical outcomes, anatomical and diffusion weighted imaging from a large dataset (the NCAA/DOD CARE Consortium Advanced Research Core). The plan is to build predictive modeling tools available on brainlife.io that can be freely used by clinicians around the world to help in patient care management. Opportunities exist to join several additional concussion, machine learning, informatics and neuroimaging projects with the labs of Drs. Port and Pestilli. The position will be based in Dr. Port’s new, state-of-the-art laboratory within the dedicated Research Center for Elite Athletic Development in the new 66,000 square-foot South-End-Zone edition to Indiana University’s Memorial Stadium (https://iuhoosiers.com/facilities/the-excellence-academy/21 https://president.iu.edu/media/photos/2018/excellence-academy-dedication/in…) A major research university, Indiana University currently enrolls over 38,000 undergraduates and 10,000 graduate and professional students on the Bloomington campus, and has over 114,000 students in the University system. The School of Optometry, Program in Neuroscience and Cognitive Science Program are internationally recognized, vibrant research programs with a very collegial environment. The Department of Psychological and Brain Sciences has a research dedicated 3T Prisma, which Dr. Port uses regularly. A diverse community, Bloomington is located in a beautifully wooded and hilly area of the state, where cultural and recreational opportunities abound, housing costs are low, schools are excellent, and commute times are short. Additional information on the community of Bloomington can be found at https://www.visitbloomington.com/. The Postdoctoral Fellow position requires a PhD in Neuroscience, Computer Science, Engineering, Informatics, Vision Science or related scientific field by the time of appointment. For the Research Associate position, a minimum of a Masters degrees and 5+ year of appropriate work experience is required. Salary and rank will be commensurate with qualifications and experience. For consideration, please submit a letter of application, curriculum vita, and the names and contact information for at least three references. Interested candidates should review the application requirements and submit their application at: http://indiana.peopleadmin.com/postings/10224 Applications received by Jan 11, 2021, will be assured priority consideration; however, the search will remain open until the position is filled. Best regards, Franco FRANCO PESTILLI, PhD | Associate Professor Department of Psychology <https://liberalarts.utexas.edu/psychology/index.php> | College of Liberal Arts <https://liberalarts.utexas.edu/> | The University of Texas at Austin <https://www.utexas.edu/> he/him | pestilli(a)utexas.edu <mailto:pestilli@utexas.edu> | web <https://liberalarts.utexas.edu/psychology/faculty/fp4834> | github <https://github.com/francopestilli> | brainlife.io <https://brainlife.io/>

Dec. 22, 2020

Tenure-track faculty position in computational/theoretical neuroscience at UChicago

by Brent Doiron

*Tenure-track Faculty in Computational/Theoretical NeuroscienceThe University of Chicago: Biological Sciences Division: Department of Neurobiology* Position Description The University of Chicago's Grossman Center for Quantitative Biology and Human Behavior and the Department of Neurobiology seek faculty in computational/theoretical neuroscience. The appointee will be a core member of the newly-launched Grossman Center for Quantitative Biology and Human Behavior and will lead a ‘dry’ computational lab alongside a growing group of other computational neuroscientists. The Grossman Center seeks faculty who will establish deep and extensive collaborations with the vibrant experimental neuroscience community at the University of Chicago. Those developing computational models and analysis methods at the cellular, circuits, systems, or cognitive levels are especially welcome to apply. Appointment as a tenure-track assistant professor is expected, but we will consider appointments as a tenured associate or full professor. The University of Chicago is currently engaged in a major expansion in neuroscience, with computational neuroscience being an area of focus. The University offers a rich intellectual environment that includes a strong translational neuroscience community and affiliations with Argonne National Laboratory and the Marine Biological Laboratory in Woods Hole. The Division, other academic units of the University, and the School of Medicine, are all contained within one compact campus in Chicago's Hyde Park. Appointees will have access to state-of-the-art core facilities and to outstanding colleagues and graduate students affiliated with numerous degree-granting programs within and outside the biological sciences. Prior to the start of employment, qualified applicants must have a doctoral degree or equivalent. To be considered, those interested must apply through the University of Chicago’s Academic Recruitment job board, which uses Interfolio to accept applications: http://apply.interfolio.com/82120. Applicants must upload a CV including a bibliography, contact information for 3 references, a statement outlining research goals, and a teaching statement that can include a description of the candidate’s experience in teaching diverse students [the University’s Diversity Statement can be found at https://provost.uchicago.edu/statements-diversity] Review of complete applications will begin February 1 2021 and continue until the position is filled. Equal Employment Opportunity Statement We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages diverse perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange. The University’s Statements on Diversity are at https://provost.uchicago.edu/statements-diversity. The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, status as an individual with a disability, protected veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination. Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-1032 or email equalopportunity(a)uchicago.edu with their request. -- Brent Doiron Professor of Neurobiology and Statistics Director of the Grossman Center for Quantitative Biology and Human Behavior University of Chicago Chicago IL

Dec. 21, 2020

Postdoctoral Position at MassachusettsGeneral Hospital

by Xin Yu

*Postdoctoral Research Fellow Position at Massachusetts General Hospital* The Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology at Massachusetts General Hospital is offering a postdoctoral position based on an NIH-funded Brain Initiative project developing novel multi-modal neuroimaging methodology in animal models. This position is open from Jan 1st. 2021 until filled. Potential candidates will be considered based on the following two research directions: *Research Direction #1 Multi-modal neuroimaging in animal brains, (Biologists/biomedical engineers/electrophysiologists) * a) Implement the MRI/EEG/calcium recording methods to specify brain state fluctuation correlated to pupil dynamics in awake rodents b) Target specific nuclei with deep brain optogenetic stimulation methods to study circuit-specific brain state neuromodulation. c) Develop an advanced fiber-optic imaging device for MRI compatible concurrent brain dynamic signal recordings, e.g., Ca2+, Glutamate, dopamine, and other neuromodulators. Experience with viral transfection, 2-PM or optical fiber recordings, or *in vivo. / in vitro. *electrophysiology in animal models (rodents) is highly desirable. The candidates should bear experience or strong interests in brain functional imaging, e.g. task-based BOLD fMRI. *Research Direction #2 Advanced fMRI and computational method development (Bio-engineering and computational neuroscientists)* a) Develop and optimize the high spatiotemporal fMRI method with high field MRI (>11.7T). b) Advanced resting-state fMRI analysis method development based on the neural network-based learning schemes. (being familiar with recurrent neural network design and implementation, e.g. ESN, GRU, et al.) c) Machine learning-based multi-modal brain signal dynamic signal analysis, e.g. LFP, Calcium, fMRI, pupil dynamics, et al. Candidates with strong computational skills and fMRI data processing experience are highly encouraged to apply for this position. The candidate should have strong teamwork skills to fit in a multi-disciplinary group. Please send your CV, contact information of three references, and a cover letter describing your background, interests, and research goals to Dr. Yu by e-mail: xyu9(a)mgh.harvard.edu. Please include “Postdoc Application for Multi-modal fMRI” in the subject line of your email. We welcome trainees with high motivation, curiosity, and scientific maturity. Also, Dr. Yu’s lab has extensive experience to support trainees to apply for international scholarships and help junior researchers to build their academic careers. Here is the selected publication in 2019-20 from Yu lab: 1. Chen Y, Sobczak F, Pais-Roldán P, Schwarz C, Koretsky AP, Yu X. Mapping the Brain-Wide Network Effects by Optogenetic Activation of the Corpus Callosum. Cereb Cortex. 2020 Oct 01; 30(11):5885-5898. PMID: *32556241 <https://www.ncbi.nlm.nih.gov/pubmed/32556241>*. 2. Sobczak F, He Y, Sejnowski TJ, Yu X. Predicting the fMRI Signal Fluctuation with Recurrent Neural Networks Trained on Vascular Network Dynamics. Cereb Cortex. 2020 Sep 17. PMID: *32940658 <https://www.ncbi.nlm.nih.gov/pubmed/32940658>*. 3. Drew PJ, Mateo C, Turner KL, Yu X, Kleinfeld D. Ultra-slow Oscillations in fMRI and Resting-State Connectivity: Neuronal and Vascular Contributions and Technical Confounds. Neuron. 2020 09 09; 107(5):782-804. PMID: *32791040 <https://www.ncbi.nlm.nih.gov/pubmed/32791040>*. 4. Pais-Roldán P, Takahashi K, Sobczak F, Chen Y, Zhao X, Zeng H, Jiang Y, Yu X. Indexing brain state-dependent pupil dynamics with simultaneous fMRI and optical fiber calcium recording. Proc Natl Acad Sci U S A. 2020 03 24; 117(12):6875-6882. PMID: *32139609 <https://www.ncbi.nlm.nih.gov/pubmed/32139609>*. 5. Ovsepian SV, Jiang Y, Sardella TCP, Malekzadeh-Najafabadi J, Burton NC, Yu X, Ntziachristos V. Visualizing cortical response to optogenetic stimulation and sensory inputs using multispectral handheld optoacoustic imaging. Photoacoustics. 2020 Mar; 17:100153. 6. Handwerker J, Pérez-Rodas M, Beyerlein M, Vincent F, Beck A, Freytag N, Yu X, Pohmann R, Anders J, Scheffler K. A CMOS NMR needle for probing brain physiology with high spatial and temporal resolution. Nat Methods. 2020 01; 17(1):64-67. PMID: *31768059 <https://www.ncbi.nlm.nih.gov/pubmed/31768059>*. 7. Chen X, Sobczak F, Chen Y, Jiang Y, Qian C, Lu Z, Ayata C, Logothetis NK, Yu X. Mapping optogenetically-driven single-vessel fMRI with concurrent neuronal calcium recordings in the rat hippocampus. Nat Commun. 2019 11 20; 10(1):5239. PMID: *31748553 <https://www.ncbi.nlm.nih.gov/pubmed/31748553>*. 8. He Y, Wang M, Yu X. High spatiotemporal vessel-specific hemodynamic mapping with multi-echo single-vessel fMRI. J Cereb Blood Flow Metab. 2020 Oct; 40(10):2098-2114. PMID: *31696765 <https://www.ncbi.nlm.nih.gov/pubmed/31696765>*. 9. Chen Y, Pais-Roldan P, Chen X, Frosz MH, Yu X. MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording. Nat Commun. 2019 06 10; 10(1):2536. PMID: *31182714 <https://www.ncbi.nlm.nih.gov/pubmed/31182714>*. 10. Pais-Roldán P, Edlow BL, Jiang Y, Stelzer J, Zou M, Yu X. Multimodal assessment of recovery from coma in a rat model of diffuse brainstem tegmentum injury. Neuroimage. 2019 04 01; 189:615-630. PMID: *30708105 <https://www.ncbi.nlm.nih.gov/pubmed/30708105>*.

Dec. 21, 2020