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Frontiers Research Topic on Neuroscience of response inhibition

by Vassilis Cutsuridis

Announcement of the Frontiers Research Topic --------------------------------------------------------------------------------------------------------------------------------------------------------- Neuroscience of response inhibition: bridging scales with experiments and computational modelling ---------------------------------------------------------------------------------------------------------------------------------------------------------- Response inhibition is the ability to override a planned or an already initiated response. It is the hallmark of executive control, because it allows people to flexibly adjust their behaviour according to their goals. In everyday life, there are many examples of response inhibition, such as stopping yourself when you are about to cross a street where a speeding car is approaching. Response inhibition deficits favour impulsive behaviours which may be detrimental to an individual’s life and it has been linked to disorders such as attention-deficit/hyperactivity disorder, obsessive-compulsive disorder, schizophrenia, and substance abuse disorders. In this Research Topic, we welcome papers critically evaluating the existing methods of response inhibition, introducing new experimental and theoretical approaches that probe particular parts of brain circuitry and unravel neuronal mechanisms as candidates of impulse control. We welcome scientists from different fields: from neuroscience of microcircuits to systems neuroscience of large-scale networks and behavioural neuroscience. The work can be experimental or computational. Commentaries and reviews on innovative key issues of response inhibition are also welcome. We invite you to submit a manuscript until November 30, 2018. Contributions will be published as soon as they are accepted and synchronously gathered in the Research Topic volume. For more information, do not hesitate to contact us (email of Vassilis Cutsuridis: vcutsuridis(a)gmail.com <digitalesbad(a)gmail.com>). The organisers Vassilis Cutsuridis (University of Lincoln) Ganesan Venkatasubramanian (National Institute of Mental Health and Neurosciences, Bangalore, India)

Oct. 2, 2018

New temporal multiple kernel learning method for characterizing relating SC to connectivity dynamics and Brain state switching

by Dipanjan

Dear all, It is my pleasure to share with you a very recent methods and data driven modelling paper from our lab on how Resting State Dynamics Meets Anatomical Structure: Temporal Multiple Kernel Learning (tMKL) Model to explore SC-dFC-FC tripartite relationship published in Neuroimage. https://www.sciencedirect.com/science/article/pii/S1053811918318597?via%3Di… The proposed model uses spectral graph theory techniques to partitions aspects of the whole-brain dynamics essentially into two parts: (i) characterizing temporal dynamics through identification of latent transient states, and (ii) linking them to the underlying structural geometry. These two aspects are captured using a novel blend of unique methods. The proposed solution does not make strong assumptions about the underlying data and is generally applicable to resting or task data for learning subject-specific state transitions and for successfully characterizing SC-dFC-FC relationship through a unifying framework. MATLAB code for the proposed method can be downloaded from: https://github.com/SriniwasGovindaSurampudi/tMKL Any comments/questions/suggestions on the method/code are of course welcome. Regards, Dipanjan

Oct. 2, 2018

Several Openings, New Lab. Systems Neuroscience.

by Carmen Varela

We are looking for researchers (undergraduate to postdoc) to join a new systems neuroscience laboratory that will open in the rapidly growing Jupiter campus of Florida Atlantic University (FAU) in 2019. Under the direction of Dr. Carmen Varela, the lab will seek to discover fundamental cellular and network mechanisms that contribute to cognitive behavior, with a focus on learning and memory and on the role of the neuronal circuits formed by the thalamus https://www.thethalamus.org/ We will rely heavily on extracellular recordings in behaving rodents and quantitative analyses of cellular activity and local field potentials, in order to investigate how thalamic networks contribute to memory retrieval, problem solving, and sleep-dependent memory consolidation. If you are passionate about these topics we would love for you to join us and be part of the founding projects of the lab! *General requirements: * Outstanding interpersonal and communication skills, demonstrated initiative and dedication, ability to learn fast. Hands-on research experience in neuroscience preferred, particularly with rodent models. Knowledge of MATLAB (and/or other programming languages) and computational skills (signal processing, statistics) desirable. Candidates selected for an interview will be asked to provide contact information for two references. Start date is flexible from January 2019. *What you get: * · Research experience in behavioral and cognitive neuroscience, electrophysiology, optogenetics, fiber photometry. · Mentorship and guidance to help you achieve your scientific and training goals. The lab is located in the Jupiter campus of FAU, an expanding neuroscience hub that also holds our partners the Max Planck Florida Institute for Neuroscience and Scripps Research Institute. If interested in joining as a graduate student, there are several programs within FAU and with the Max Planck and Scripps (http://www.ibrain.fau.edu/gradneuro/program.html) Application deadlines for graduate programs in the Fall of 2018. *Interested candidates please send a CV and a brief description of research skills and interests to: carmenv(a)mit.edu <carmenv(a)mit.edu> *

Oct. 2, 2018

PhD opportunities at the Universities of Bath and Exeter

by Purcell, Sarah

Dear all, The Universities of Bath and Exeter are seeking applications for PhD candidates for two biology/medicine modelling projects. Both projects will use a combination of mathematical modelling and data analysis (possibly with some data collection for interested applicants). The studentship will cover 3.5 years, with a start date of September 2019. However, this is open for EU students only. The first project will involve multi-scale modelling of skeletal muscle bioenergetics, with applications to deficits in cystic fibrosis. The student would primarily be based at the University of Exeter (with Dr. Kyle Wedgwood & Prof. Craig Williams) with secondments at the University of Bath (with Dr. James Betts). For more information, see here: http://www.exeter.ac.uk/studying/funding/award/?id=3236 The second project will investigate ion channel mutations associated with dementia. The student would primarily be based at the University of Bath (with Prof. Alain Nogaret) with secondments at the University of Exeter (with Prof. Andy Randall, Dr. Kyle Wedgwood). For full details of the project, please visit http://www.gw4biomed.ac.uk/available-projects-2/neuroscience-and-mental-hea… and select the project entitled "In-depth understanding of dementia-associated changes to neuronal signalling" Best wishes, Dr. Kyle Wedgwood MRC Research Fellow Centre for Biomedical Modelling & Analysis College of Engineering, Mathematics and Physical Sciences University of Exeter Living Systems Institute Stocker Road EX4 4QD ________________________________________________________________

Oct. 2, 2018

Postdoctoral Fellow in Multifactorial Brain Analysis of Amyotrophic Lateral Sclerosis

by Yasser Iturria Medina

We are looking for a highly motivated postdoctoral student, for joining the *Neuroinformatics for Personalized Medicine* lab (NeuroPM) at the Montreal Neurological Institute (McGill University, Montreal, Canada) and the Kalra lab for Neuroimaging and ALS Research (University of Alberta, Edmonton, Canada). The postdoc will be under the supervision of Professors Yasser Iturria-Medina and Sanjay Kalra, and will be expected to collaborate with multiple associated groups. The project, for one year and potentially extendable for another year, includes the analysis of direct multifactorial brain interactions and intra-brain network spreading of aberrant effects in Amyotrophic Lateral Sclerosis. The NeuroPM lab (http://www.neuropm-lab.com/) is affiliated with the Healthy brain for Healthy Lives (HBHL) initiative (*https://www.mcgill.ca/hbhl/ <https://www.mcgill.ca/hbhl/>*), the Ludmer Center (http://ludmercentre.ca/) and the McConnell Brain Imaging Center (https://www.mcgill.ca/bic/) involving computationally intensive and interdisciplinary research on the brain. The MNI is an internationally renowned institution, characterized by the integration of research and patient care. The Kalra Lab ( http://www.ualberta.ca/ALS/research/) has the mission of improving our understanding of ALS biology through brain imaging and translational research. It is the central coordinating site for the Canadian ALS Neuroimaging Consortium (CALSNIC), a multicenter research platform for the collection of harmonized imaging and behavioural data. Interested candidates should have a solid background in brain imaging and Matlab. Experience in neurodegeneration and brain computational modeling will be an asset. Interested persons should send their CV, a cover letter stating research interests, and two reference letters. The competition will remain open until the position is filled. *Contact*: Yasser Iturria Medina, Emails: yasser.iturriamedina(a)mcgill.ca Sanjay Kalra, Email: kalra(a)ualberta.ca -- Yasser Iturria Medina, PhD. Montreal Neurological Institute, McGill University Montreal, Canada H3A 2B4, Phone # 514-398-1524 Lab: http://www.neuropm-lab.com/

Oct. 1, 2018

Graduate Student openings in the UCR Brain Game Center and Sensory Learning Lab

by Aaron Seitz

Professor Aaron Seitz in the Department of Psychology at UC Riverside has several openings for graduate students. Students can work in one or both of the Perception and Learning lab and the Brain Game Center. The Perception and Learning lab conducts basic research on perception, learning and memory using a variety of approaches including advanced Psychophysics, EEG, and fMRI, and computational methodologies. The UCR Brain Game Center is a unique research unit that focuses on translational psychology and neuroscience work where we exploit the potential of consumer technologies to conduct research at large scale. This involves running hundreds to many thousands of participants on research studies designed to develop better measurements of perceptual and cognitive abilities as well as new training tools for these skills. To date we have developed numerous approaches addressing vision, hearing, working memory, executive function, and fluid intelligence. In both labs we use compu! tational modeling and machine learning as well as standard data analysis approaches. For more information on research in the Seitz labs please see http://faculty.ucr.edu/~aseitz/ and http://braingamecenter.ucr.edu. Prospective graduate students should send an email to aseitz(a)ucr.edu with their CV, and description of research interests. Successful applicants will receive funding toward their Ph.D. for at least 5 years. Please see the following websites for more information about the Psychology (https://psych.ucr.edu) or Neuroscience (http://neuro.ucr.edu) graduate programs. -Aaron ************************************************** Aaron Seitz, Ph.D. Professor of Psychology Director of UCR Brain Game Center University of California, Riverside 900 University Ave. Riverside, CA 92521 Ph: (951) 827-6422 Fax: (951) 827-3985 Email: aseitz(a)ucr.edu Web: http://faculty.ucr.edu/~aseitz/ BGC: http://braingamecenter.ucr.edu **************************************************

Oct. 1, 2018

Tenure-track faculty position in Computation Neuroscience at Western University, Canada

by Jorn Diedrichsen

Supported by BrainsCAN, a $66M grant from the Canadian government (www.uwo.ca/brainscan<http://www.uwo.ca/brainscan>), Western University is expanding it’s strength in Neuroscience with a new tenure-track faculty position (Assistant or Associate Professor) in Computational Neuroscience. Successful candidates will join the Brain and Mind Institute (www.uwo.ca/bmi<http://www.uwo.ca/bmi>), one of the leading centres in cognitive Neuroscience in Canada, with a full range of ultrahigh field, research-dedicated MRI scanners (3T, 7T, 9.4T) and state-of-the-art laboratories for cognitive, behavioural, and neurophysiological testing in humans, non-human primates and rodents. The academic appointment of the candidate will be, depending on the candidate’s background, in the Department for Applied Mathematics, Statistics, or Computer Science. The deadline for the position in Computational Neuroscience is November 1st: https://brainscan.uwo.ca/work_with_us/vacancies/index.html Jörn Diedrichsen Western Research Chair Brain Mind Institute Department of Computer Science Department of Statistics Email: jdiedric(a)uwo.ca<mailto:jdiedric@uwo.ca> Tel: 1-519-661-2111 x86994

Sept. 29, 2018

Postdoctoral research in theoretical neuroscience

by Brent Doiron

The Doiron group at the University of Pittsburgh is currently seeking up to three postdoctoral fellows to work on cutting edge problems in theoretical neuroscience. Research topics include 1) Large-scale collaboration on modeling diverse inhibitory circuits in mouse V1. The research will be in collaboration with the Columbia theory center (Ken Miller, Larry Abbott, Misha Tsodyks, and Liam Paninski) as well as experimental labs at Berkeley (Adesnik lab, Ji lab) , UCSF (Scanziani lab) and Caltech (Cai lab). 2) Modeling population activity in the visual system and its modulation through top-down cognitive processes. 3) Modeling the formation and stability mechanics of learning in recurrently coupled cortical networks. All projects will involve heavy collaboration with several prominent experimental groups both in Pittsburgh as well as abroad. The positions are 3 year terms (contingent upon satisfactory progress) with competitive salary and benefits packages offered by the University of Pittsburgh. The successful candidate will join the Mathematics department at the University of Pittsburgh and will have strong ties to the Center for the Neural Basis of Cognition in Pittsburgh (joint between Pitt and Carnegie Mellon University). Candidates should have a Ph.D. in computational neuroscience, mathematics, physics, or engineering and have an excellent track record of scholarship. The University of Pittsburgh is an affirmative action/equal opportunity employer and encourages applications from under-represented groups. Interested persons should send their CV, a cover letter stating research interests and career goals, and names and contact information of two references to: bdoiron(a)pitt.edu . The competition will remain open until the positions are filled. -- Professor of Mathematics Center for the Neural Basis of Cognition University of Pittsburgh 301 Thackeray Hall Pittsburgh, PA, 15260 www.math.pitt.edu/~bdoiron

Sept. 29, 2018

Faculty position in computational neuroscience at the University of Pittsburgh

by Brent Doiron

Dear Computational neuroscience community The Dietrich School at the University of Pittsburgh invites applications for two tenure-track faculty positions at the Assistant Professor level in *Mathematical and Computational Life Sciences *to begin in the fall term of 2019. Successful candidates will be placed in the departments most suitable for their backgrounds and research programs from among the Departments of Mathematics, Biology, Neuroscience, Physics, and Chemistry. We seek outstanding scientists who will enhance and complement our existing strengths and who will collaborate with members of our sizable neuroscience, biology, biophysics, and biochemistry communities. One position is in *Mathematical and Computational Neuroscience. *Candidates working on the following topics are especially encouraged to apply: - Circuits and information flow in neuroscience - Neuronal and population dynamics - Synaptic mechanisms and dynamics - Neuronal membrane properties and ion channel function The other position is in *Mathematics and Theory of Biological Processes*. Candidates working on the following topics are especially encouraged to apply: - Mathematical ecology - Evolutionary theory - Cellular sensing and signal processing - Epigenetic and gene network dynamics The University of Pittsburgh is an active center for interdisciplinary research in the life sciences offering exciting opportunities for collaborations across departments as well as with our highly ranked medical school. The University is currently ranked third in the nation in total NIH funding, and the city of Pittsburgh is often voted “most livable” in the nation. These positions represent part of a vision to grow our community of researchers at the interface of mathematics, physics, chemistry and the life sciences. Successful candidates will have a Ph.D. and should demonstrate substantial research accomplishment and dedication to teaching. They will be expected to establish an extramurally funded research program, train graduate students, and actively participate in undergraduate education. *Review of applications will begin on October 23, 2018, *and will continue until the positions are filled*. *Applicants can apply online at: https://facultysearch.as.pitt.edu/apply/index/MjQy. Candidates should submit (a) a cover letter, (b) a CV, (c) a statement of research accomplishments and future plans, (d) a brief description of teaching interests, (e) a brief description of how your research, teaching or service demonstrates a commitment to diversity and inclusion, and (f) at least three letters of reference (for each reference, you will have the opportunity to input an email address through Interfolio’s Online Application system and a notification will be sent to the designated address with instructions). The positions are pending budgetary approval. The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity and diversity. EEO/AA/M/F/Vets/Disabled. Person to Contact: Erika Carpio 139 University Place Room 302 Pittsburgh, PA 15206 412-624-8361 -- Professor of Mathematics Center for the Neural Basis of Cognition University of Pittsburgh 301 Thackeray Hall Pittsburgh, PA, 15260 www.math.pitt.edu/~bdoiron

Sept. 29, 2018

job opening in neural dynamics and control

by Obermayer, Klaus, Prof. Dr.

Dear moderator, can post our job announcement below on the neuroinformatics mailing list? Thank you very much! Best regards Klaus Obermayer ------------------------------------------------------------------------------------------------------------------------------------------------ Neural Information Processing Group @ Technische Universität Berlin Research Assistant (PhD Position) in Computational Neuroscience Brain network models: Dynamics and Control Salary grade E13 (TV-L Berliner Hochschulen) Duration: max. 4 years Starting date: January 1st, 2019 Working field: The successful candidate is supposed to work on the analysis and simulation of calibrated whole-brain networks using neuronal mass models and on the design and evaluation of novel control schemes for the stabilization of and the switching between their dynamical states. She/he will be part of the Collaborative Research Center "Control of self-organizing nonlinear systems: Theoretical methods and concepts of application" (https://www.itp.tu-berlin.de/sfb910/ sonderforschungsbereich_910/sonderforschungsbereich_910/) as well as the Bernstein Center for Computational Neuroscience Berlin (https://www.bccn-berlin.de/) The candidate is also expected to interact with clinical scientists who are interested in the non-invasive manipulation of the whole-brain dynamics using transcranial current stimulation. Requirements: Successfully completed university degree (Master, Diplom, or equivalent) in Computational Neuroscience, Computer Science, Mathematics, Physics, or related fields; in-depth knowledge in non-linear dynamics and stochastic processes; very good programming and English language skills. How to apply: Please send your application with the usual documents (CV, motivation letter, transcripts of records, certificates, and the names of two persons who can provide recommendation letters) to Prof. Dr. Obermayer, FG Neuronale Informationsverarbeitung, Sekr. MAR 5-6, Marchstr. 23, 10587 Berlin, Germany, or by e-mail to klaus.obermayer(a)tu-berlin.de. For information about the research group see https://www.ni.tu-berlin.de/ Please send copies only. Original documents will not be returned. Aplication deadline: 26. 10. 2018 Reference number: IV-570/18

Sept. 28, 2018