October 2018 - Comp-neuro - lists.cnsorg.org

PhD opportunities at the MCEN group at the Basque Center of Applied Mathematics (Bilbao, Spain)

by Maurizio De Pitta

Please share with your colleagues and anyone who could be interested. The Group of Mathematical, Computational and Experimental Neuroscience (MCEN; http://www.bcamath.org/en/research/lines/MCEN/description) at the Basque Center of Applied Mathematics (BCAM; http://www.bcamath.org/en/) in Bilbao (Spain) is seeking outstanding PhD students to work on several projects at the intersection of computational neuroscience, mathematical topology, biophysics and translational science. PhD projects currently available include (but are not limited to) : (Track A) 1. Control and tracking stability boundaries of neurons in real time via closed-loop computer- controlled electrophysiology. This will lead to intelligent machine brain interfaces, such as deep brain stimulators that can determine unstable states that lead to pathological oscillations (like in epilepsy); 2. Multiscale modeling of the biomolecular machinery that controls the various modes of neurotransmitter release for efficient synaptic communication. This includes feedback processes, such as the endocannabinoid system, that control the speed and frequency by which synaptic neurotransmitters are released. This critical process is thought to control pathological brain states; (Track B) 3. Mathematical modeling and development of analytical tools to study neuron-glial interactions (NGIs), from subcellular to network levels. Focus is both on mechanisms of learning at synaptic level and how NGIs could shape dynamics of cortical circuits in the healthy and diseased brain (More info: https://goo.gl/pJXEYJ) 4. Study of early cellular pathological markers for Alzheimer’s disease, with emphasis on neuron-glial interactions. The project is part of a strategic collaboration between BCAM/MCEN and Achucarro – the Basque Center for Neuroscience – and envisages a close collaboration with Dr. Carlos Matute’s group to test predictions from theoretical models in mouse models of Alzheimer’s disease (see also: https://goo.gl/Uifv2J) A fully-funded PhD scholarship of 4+1 years may be offered on competitive basis for ANY of the above projects (deadline : **Oct 29th, 2018**; 15:00 CET ; Info/Application : https://goo.gl/7CzNQr) A fully-funded PhD scholarship of 3 years is currently available for Project 4 ONLY (deadline : **Nov 6th, 2018**; 14:00 CET ; Info : https://goo.gl/Uifv2J; Application website : https://goo.gl/z72RzC) Candidates that are interested in any of the above topics, or would like to pursue a PhD in mathematical neuroscience are welcome to contact Drs. Serafim Rodrigues (Track A ; Webpage : https://goo.gl/tP9PBt; contact : srodrigues(a)bcamath.org) and Maurizio De Pittà (Track B ; Webpage : https://goo.gl/pJXEYJ; contact: mdepitta(a)bcamath.org) ----- Maurizio De Pitta' Research Fellow MCEN -- Group of Mathematical, Computational and Experimental Neuroscience BCAM -- Basque Center of Applied Mathematics https://sites.google.com/site/mauriziodepitta/home

Oct. 22, 2018

PhD Studentship at the University of Exeter: Building a model of the HypothalamicPituitary-Gonadal (HPG) axis

by Tsaneva-Atanasova, Krasimira

Building a model of the HypothalamicPituitary-Gonadal (HPG) axis, BBSRC SWBio, PhD in Mathematics studentship (Funded) Ref: 3285 About the award Supervisors Lead Supervisor Professor Krasimira Tsaneva-Atanasov<http://emps.exeter.ac.uk/mathematics/staff/kt298>a, Department of Mathematics, College of Engineering, Mathematics and Physical Sciences, University of Exeter Additional Supervisors Professor Craig McArdle<http://www.bristol.ac.uk/clinical-sciences/people/craig-a-mcardle/index.html>, University of Bristol Dr Margaritis Voliotis<http://emps.exeter.ac.uk/mathematics/staff/mv286>, University of Exeter Location: University of Exeter, Streatham Campus, Exeter EX4 4QJ The SWBio DTP<http://www.bris.ac.uk/swbio/> is one of the 12 Doctoral Training Partnerships funded by the BBSRC to provide PhD training in areas of their strategic relevance. The SWBio DTP is a consortium comprising the Universities of Bristol (lead), Bath, Cardiff, Exeter, and Rothamsted Research. Together, these institutions present a distinctive cadre of bioscience research staff and students with established international, national and regional networks and widely recognised research excellence. The award: There are over 30 (including up to 5 CASE studentships) fully-funded 4 year studentships* available to start in September 2019 across a wide range of biosicence academic disciplines. This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP)<http://www.bristol.ac.uk/swbio/>. Up to 6 fully-funded studentships are being offered to start in September 2019 at the University of Exeter. Project Description: Gonadotropin-releasing hormone (GnRH) is secreted from hypothalamic neurones to control secretion of the gonadotropin hormones LH and FSH form the anterior pituitary, and thereby mediates central control of reproduction. It secretes in pulses and its effects are dependent on pulse characteristics (particularly pulse frequency). One of the most important recent discoveries in the field of reproduction is that of the KNDy system. This is a peptidergic neuronal oscillator that drives pulsatile GnRH secretion. It also mediates feedback effects of gonadal steroid hormones that are essential for key reproductive processes such as the timing of puberty and seasonal breeding (i.e. in farm animals) and the fine-tuning of gonadotropin secretion across the ovarian cycle. All of these components (hypothalamic pulse generator/pituitary pulse decoder/gonads) are absolutely essential for human reproduction so it is perhaps not surprising that all three are sites for therapeutic intervention, just as perturbation of any of them can cause infertility in disease states. We are convinced that mathematical and statistical approaches are required to fully understand such a complex system. To this end we have already generated a sophisticated mathematical model of the neuronal oscillator that we have trained on wetlab. data and are now using to explore possible mechanisms for modulation by gonadal steroids. Similarly, we have developed a mathematical model for the decoding of pulse dynamics by pituitary gonadotropes and have used this to explore cell-cell variability in responses to GnRH and its impact on information transfer. We now plan to take a similar approach to modelling effects of gonadotropin hormones on gonadal function, where we will have to introduce population dynamics as an additional feature (i.e. growth of granulosa cells before ovulation and formation of luteal cells thereafter). We then plan to simplify these sub-system models so that the components can be assembled into a meaningful model of the entire hypothalamo-pituitary-gonadal system. In this project the student will learn: • Mathematical modelling of the hypothalamic pulse generator, the pituitary pulse decoder and the effects of LH and FSH on gonadal cells. • Numerical optimisation by performing parameter fitting and sensitivity analysis using combination of available experimental data sets to parametrise and validate model components. • Simplification of the sub-system models (as informed by sensitivity analysis) and again, training on system wet-lab data. • Computational methods that allow the generation of testable model predictions regarding the reproductive system and its components across the lifespan. Eligibility To be eligible for a fully-funded studentship, you must meet both the academic and residence criteria. For UK/EU nationals who meet the residency requirements outlined by the BBSRC, the studentship will cover funding for 4 years (48 months) as follows. These awards might be available to part-time students, but only in exceptional circumstances. It is recommended you speak to the lead supervisor prior to submitting an application. • a stipend at the standard Research Council UK rate; currently £14,777 per annum for 2018-2019 • research and training costs • tuition fees (at the standard Research Councils UK rate) • additional funds to support fieldwork, conferences and a 3-month internship Please refer to the regulations<http://www.legislation.gov.uk/uksi/2007/779/pdfs/uksi_20070779_en.pdf> or Annex 1 of the Research Council Training Grant Guide<https://www.ukri.org/files/legacy/publications/rcuk-training-grant-guide-pd…> to confirm that you meet the residence criteria for a fully-funded studentship. Any further queries in relation to residency must be directed to the institution that you are applying to. Entry requirements Applicants should have obtained, or be about to obtain, a First or Upper Second Class UK Honours degree, or the equivalent qualifications gained outside the UK, in an appropriate area of science or technology. Applicants with a Lower Second Class degree will be considered if they also have Masters degree or have significant relevant non-academic experience. In addition, due to the strong mathematical component of the taught course in the first year and the quantitative emphasis in our projects, a minimum of a grade B in A-level Maths or an equivalent qualification or experience is required. If English is not your first language you will need to have achieved at least 6.5 in IELTS and no less than 6.5 in any section by the start of the project. Alternative tests may be acceptable, please see http://www.bristol.ac.uk/study/language-requirements/profile-c/. Students from EU countries who do not meet the residency requirements may still be eligible for a fees-only award but no stipend. Applicants who are classed as International for tuition fee purposes are not eligible for funding. Please refer to the regulations<http://www.legislation.gov.uk/uksi/2007/779/pdfs/uksi_20070779_en.pdf> or Annex 1 of the Research Council Training Grant Guide<https://www.ukri.org/files/legacy/publications/rcuk-training-grant-guide-pd…> to confirm that you meet the residence criteria for a fully-funded studentship. The four universities have a very limited number of fully-funded 4 year studentships that EU nationals who do not meet the residency requirements would be eligible for. Please contact us for for more information. How to apply Apply now Please be aware you will be asked to upload the following documents: * CV * Letter of application outlining your academic interests, prior research experience and reasons for wishing to undertake the project. Please indicate your preferred project choice if applying for multiple BBSRC SWBio DTP projects. * Transcript(s) giving full details of subjects studied and grades/marks obtained. This should be an interim transcript if you are still studying. * Two academic referees - see information below about references. * If you are not a national of a majority English-speaking country you will need to submit evidence of your proficiency in English (see entry requirements above) The closing date for applications is midnight on Monday, 3 December 2018. Interviews will be held at the University of Exeter on 7 and 8 of February 2019. Reference information You will be asked to name 2 referees as part of the application process, however we will not expect receipt of references until the shortlisting stage. Your referees should not be from the prospective supervisory team. If you are shortlisted for interview, please ensure that you two academic referees email their references to the pgrenquiries(a)exeter.ac.uk<mailto:pgrenquiries@exeter.ac.uk>, 7 days prior to the interview dates. Please note that we will not be contacting referees to request references, you must arrange for them to be submitted to us by the deadline. References should be submitted by your referees to us directly in the form of a letter. Referees must email their references to us from their institutional email accounts. We cannot accept references from personal/private email accounts, unless it is a scanned document on institutional headed paper and signed by the referee. If you have any general enquiries about the application process please email pgrenquiries(a)exeter.ac.uk<mailto:pgrenquiries@exeter.ac.uk>. Project-specific queries should be directed to the primary supervisor. Selection process: Please note, the studentship selection process will take place in two stages: 1. The project supervisors will consider your application and may invite you to visit for an informal interview. You can apply for more than one BBSRC SWBio DTP project, although supervisors may take into account your interest and commitment to their particular project. If you apply for multiple projects, please indicate your preferred project choice in your letter of application. Each application for an individual project will be considered separately by the project supervisors. 2. After closure of applications, each supervisory team will then nominate their preferred applicant. A shortlist will be selected from these nominations and shortlisted applicants will be invited for interview on a selection day at the University of Bristol. Please note that nomination by a project supervisor therefore does not guarantee the award of a studentship. Data Protection During the application process, the University may need to make certain disclosures of your personal data to third parties to be able to administer your application, carry out interviews and select candidates. These are not limited to, but may include disclosures to: * the selection panel and/or management board or equivalent of the relevant programme, which is likely to include staff from one or more other HEIs; * administrative staff at one or more other HEIs participating in the relevant programme. Such disclosures will always be kept to the minimum amount of personal data required for the specific purpose. Your sensitive personal data (relating to disability and race/ethnicity) will not be disclosed without your explicit consent. Summary Application deadline: 3rd December 2018 Value: Tuition fees and an annual stipend allowance at Research Council rates, currently £14,777 per year for 2018-19 Duration of award: per year Contact: PGR Recruitment Office pgrenquiries(a)exeter.ac.uk<mailto:pgrenquiries@exeter.ac.uk>

Oct. 22, 2018

Open Master, PhD and Postdoc positions at the "Theory of Neural Dynamics" at the MPI for Brain Research

by Tatjana Tchumatchenko

Dear friends and colleagues, I would appreciate if you could spread the word among your Students and Postdocs. My group "Theory of Neural Dynamics" at the MPI for Brain Research is looking for Master Students, PhD Students and Postdocs Master Students, PhD Students or Postdocs interested in understanding how neuronal networks work, how they respond to stimuli and what role connectivity and single neuron dynamics play for the activity of the brain. Though the focus of my research is on the theory side, my lab has close ties to experimentally oriented labs and Master projects could include both theory and experiments. We are looking for bright and hard-working students with a life-science or quantitative background (physics, math, biology etc). When applying please attach CV (with a publication record) and a current copy of academic transcripts. For more information, please contact Dr. Tatjana Tchumatchenko via email tatjana.tchumatchenko(a)brain.mpg.de https://brain.mpg.de/research/theory-of-neural-dynamics-group.html www.tchumatchenko.de

Oct. 20, 2018

Tenure Track Job at Emory University in Neural Circuit Mechanisms of Behavior

by Jaeger, Dieter

The Department of Biology in the Emory College of Arts and Science in Atlanta, GA, USA, is seeking applications for a tenure-track faculty position at the assistant or associate professor level in experimental and computational neuroscience. A strong computational neuroscience group at Emory is anchored in the Department of Biology (http://www.biology.emory.edu) and is grounded in experimental preparations and neurobiological questions about the mechanisms underlying behavior and learning. We anticipate a hire focused on innovative approaches to understanding the function of brain circuits in a behavioral context. Such approaches may include optogenetics, cellular imaging, high-density electrophysiology, network simulations, or other cutting-edge neuroscientific methods. The ability to link theory and data analysis to experimental design in order to develop more predictive models of neural activity and behavior is critical. The successful candidate is anticipated to have a PhD in a relevant science or engineering field and postdoctoral experience in neuroscience-related research, and is expected to contribute to the Biology Department's teaching mission in the context of programs in quantitative theory and methods (http://quantitative.emory.edu) and neuroscience and behavioral biology (http://www.nbb.emory.edu) Interactions with experimentalists and theorists within Emory's rich, collaborative neuroscience community are encouraged. Emory has more than 100 laboratories participating in graduate programs in Neuroscience (http://biomed.emory.edu/PROGRAM_SITES/NS/) and Biomedical Engineering (http://www.bme.emory.edu) and spanning Emory College (Biology, Psychology, Physics, Anthropology), School of Medicine, Yerkes National Primate Research Center and Georgia Institute of Technology. Emory College's Theory and Modeling of Living Systems initiative (http://livingtheory.emory.edu/) provides a broader community for interaction with theorists in the life science. Applications should include a cover letter, curriculum vitae, a research statement, a teaching statement and three reference letters. In a separate statement or in the cover letter, we also ask candidates to reflect on their efforts in mentoring and teaching students from diverse backgrounds. Applications and reference letters must be electronically uploaded through Interfolio at http://apply.interfolio.com/53691. Review of applications will begin Dec. 1, 2018. Applications received up to 30 days after, or until the positions are filled, will be given consideration. Emory University is an equal employment opportunity and affirmative action employer. Women, minorities, people with disabilities and veterans are strongly encouraged to apply. Also - one or more members of the search committee will be available for brief (10-minute) informational meetings with potential candidates during the SfN conference in San Diego in November. Please contact Sam Sober at ssober(a)emory.edu<mailto:ssober@emory.edu>. Potential candidates do not need to have submitted an application to have one of these meetings, which are intended to help applicants learn about the position, department, and neuro community at Emory. Dieter Jaeger, PhD Professor Department of Biology, Emory University 1510 Clifton Rd., Atlanta, GA 30322 404 727 8139, e-mail: djaeger(a)emory.edu<mailto:djaeger@emory.edu> http://www.biology.emory.edu/research/Jaeger ________________________________ This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments).

Oct. 19, 2018

PhD fellowships in computational neuroscience at the FMI in Basel, Switzerland

by Friedemann Zenke

The FMI PhD program now welcomes applications in computational neuroscience. Submission deadline is the 16th of November 2018. The FMI PhD program offers students the opportunity to carry out cutting-edge research in a stimulating, highly international and collaborative atmosphere. Affiliated with the Novartis Institutes for BioMedical Research and the University of Basel in Switzerland, the FMI provides interdisciplinary training and access to state-of-the-art technology platforms and high-performance computing facilities. Several research groups at the FMI offer exciting PhD projects for students with a computational background. PhD students whose primary interest is in computational neuroscience, will be able to join a new group led by Friedemann Zenke which focuses on memory formation and information processing in biologically inspired neural network models. Students will have the opportunity to directly collaborate with experimental groups in system neuroscience at the FMI (https://www.fmi.ch/Research/Neurobiology/) A wide range of theoretical and practical courses are available at both the FMI and the University of Basel. After completion of their thesis work, students are awarded a PhD from the University of Basel. Candidates should be curious about the neural underpinnings of computation and learning, have a strong analytical and quantitative background, and hold a relevant first degree in, for instance, computer science, engineering, mathematics, neuroscience, physics, psychology, or statistics. Funding is available regardless of current residence and nationality. Applications should be submitted online via https://www.fmi.ch/training/phd/apply/ Additional information PhD program: https://www.fmi.ch/training/PhD/ Zenke group (from 2019): https://www.fmi.ch/research/groupleader/zenke.html Neurobiology groups: https://www.fmi.ch/Research/Neurobiology/ For questions, please contact Elida Keller (fmiphdprogram(a)fmi.ch) -- Friedemann Zenke, PhD Sir Henry Wellcome Fellow Centre for Neural Circuits and Behaviour University of Oxford Tinsley Building Mansfield Road Oxford OX1 3SR United Kingdom https://fzenke.net

Oct. 19, 2018

CFP: FLAIRS 2019, Sarasota, FL, Datamining Track

by David Bisant

CALL FOR PAPERS FLAIRS 2019, Florida Artificial Intelligence Research Symposium Special Tracks on Data mining Sarasota, Florida https://sites.google.com/view/flairs-32homepage/home Paper submission deadline: November 19, 2018. Notifications: January 21, 2019. Camera ready version due: February 25, 2019. FLAIRS is an interdisciplinary artificial intelligence conference which especially encourages novel ideas and which features a double-blind review process. Data Mining Track This special track will be devoted to data mining with the aim of presenting new and important contributions in this area. Papers and contributions are encouraged for any work related to Data Mining. Topics of interest may include (but are in no way limited to): 1. Applications such as Intelligence analysis, medical and health applications, text, video, and multi-media mining, E-commerce and web data, financial data analysis, cyber security, remote sensing, earth sciences, bioinformatics, and astronomy. 2. Modeling algorithms such as hidden Markov models, decision trees, neural networks, statistical methods, or probabilistic methods; case studies in areas of application, or over different algorithms and approaches. 3. Feature extraction and selection. 4. Post-processing techniques such as visualization, summarization, or trending. 5. Preprocessing and data reduction. 6. Knowledge engineering or warehousing. Papers dealing with Cloud-based unstructured data or Cloud-based tool suites, such as Mahout, Amazon AWS, or Apache Spark, are also encouraged. Note: We invite original papers (i.e. work not previously submitted, in submission, or to be submitted to another conference during the reviewing process). Submission Guidelines Interested authors should format their papers according to AAAI formatting guidelines. Papers should not exceed 6 pages (or 4 pages for short paper, to be presented as a poster) and are due by November 19, 2018. FLAIRS reviewing is a double blind process. Author names and affiliations should be substituted X’d out on the submitted draft to provide double-blind reviewing. Papers must be submitted as PDF through the EasyChair conference system, which can be accessed through the main conference web site (https://sites.google.com/view/flairs-32homepage/home) Note: use your real name for your EasyChair login - your EasyChair account information is hidden from reviewers. Authors should indicate which special track they are submitting to. The proceedings of FLAIRS will be published by the AAAI. Authors of accepted papers will be required to sign a form transferring copyright of their contribution to AAAI. FLAIRS requires that there be at least one full author registration per paper.

Oct. 18, 2018

CFP: TAC | Special Issue on Automated Perception of Human Affect from Longitudinal Behavioral Data

by Pablo Barros

CALL FOR PAPERS IEEE Transactions on Affective Computing Special Issue on Automated Perception of Human Affect from Longitudinal Behavioral Data Website: https://www2.informatik.uni-hamburg.de/wtm/omgchallenges/tacSpecialIssue201… I. Aim and Scope Research trends within artificial intelligence and cognitive sciences are still heavily based on computational models that attempt to imitate human perception in various behavior categorization tasks. However, most of the research in the field focuses on instantaneous categorization and interpretation of human affect, such as the inference of six basic emotions from face images, and/or affective dimensions (valence-arousal), stress and engagement from multi-modal (e.g., video, audio, and autonomic physiology) data. This diverges from the developmental aspect of emotional behavior perception and learning, where human behavior and expressions of affect evolve and change over time. Moreover, these changes are present not only in the temporal domain but also within different populations and more importantly, within each individual. This calls for a new perspective when designing computational models for analysis and interpretation of human affective behaviors: the computational models that can timely and efficiently adapt to different contexts and individuals over time, and also incorporate existing neurophysiological and psychological findings (prior knowledge). Thus, the long-term goal is to create life-long personalized learning and inference systems for analysis and perception of human affective behaviors. Such systems would benefit from long-term contextual information (including demographic and social aspects) as well as individual characteristics. This, in turn, would allow building intelligent agents (such as mobile and robot technologies) capable of adapting their behavior in a continuous and on-line manner to the target contexts and individuals. This special issue aims at contributions from computational neuroscience and psychology, artificial intelligence, machine learning, and affective computing, challenging and expanding current research on interpretation and estimation of human affective behavior from longitudinal behavioral data, i.e., single or multiple modalities captured over extended periods of time allowing efficient profiling of target behaviors and their inference in terms of affect and other socio-cognitive dimensions. We invite contributions focusing on both the theoretical and modeling perspective, as well as applications ranging from human-human, human-computer and human-robot interactions. II. Potential Topics Given computational models, the capability to perceive and understand emotion behavior is an important and popular research topic. That is why recent special issues on the IEEE Journal on Transactions on Affective Computing covered topics from emotion behavior analysis “in-the-wild” to personality analysis. However, most of the research published by these specific calls treat emotion behavior as an instantaneous event, relating mostly to emotion recognition, and thus neglect the development of complex emotion behavior models. Our special issue will foster the development of the field by focusing excellent research on emotion models for long-term behavior analysis. The topics of interest for this special issue include, but are not limited to: - New theories and findings on continuous emotion recognition - Multi- and Cross-modal emotion perception and interpretation - Lifelong affect analysis, perception, and interpretation - Novel neural network models for affective processing - New neuroscientific and psychological findings on continuous emotion representation - Embodied artificial agents for empathy and emotion appraisal - Machine learning for affect-driven interventions - Socially intelligent human-robot interaction - Personalized systems for human affect recognition III. Submission Prospective authors are invited to submit their manuscripts electronically, adhering to the IEEE Transactions on Affective Computing guidelines ( https://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=5165369) Please submit your papers through the online system ( https://mc.manuscriptcentral.com/taffc-cs) and be sure to select the special issue: Special Issue/Section on Automated Perception of Human Affect from Longitudinal Behavioral Data. IV. IMPORTANT DATES: Submissions Deadline: 15th of January 2019 Deadline for reviews and response to authors: 06th of April 2019 Camera-ready deadline: 05th of August 2019 V. Guest Editors Pablo Barros, University of Hamburg, Germany Stefan Wermter, University of Hamburg, Germany Ognjen (Oggi) Rudovic, Massachusetts Institute of Technology, United States of America Hatice Gunes, University of Cambridge, United Kingdom -------------------------- -- Dr. Pablo Barros Postdoctoral Research Associate - Crossmodal Learning Project (CML) Knowledge Technology Department of Informatics University of Hamburg Vogt-Koelln-Str. 30 22527 Hamburg, Germany Phone: +49 40 42883 2535 Fax: +49 40 42883 2515 barros at informatik.uni-hamburg.dehttp://www.pablobarros.nethttps://www.inf.uni-hamburg.de/en/inst/ab/wtm/people/barros.htmlhttps://www.inf.uni-hamburg.de/en/inst/ab/wtm/

Oct. 18, 2018

NEURON course at SFN 2018 meeting

by Ted Carnevale

A few seats remain open for the NEURON course that we will be presenting at the SFN 2018 meeting in San Diego. However, the registration deadline is Friday, October 19--just three days from today, so you'll have to act quickly if you are interested in learning things like * why you should be using NEURON to model biological neurons and neural circuits * how to get started building models with NEURON's GUI and/or Python * advanced tips for getting the most out of using Python as NEURON's interpreter, and using NEURON's GUI for interactive modeling and debugging of models implemented with Python * using the Import3d tool to convert Neurolucida, Eutectic, and SWC morphometric data files to NEURON models * how to add new ion channels and other biophysical mechanisms to NEURON For the course description and registrion form, see https://neuron.yale.edu/neuron/static/courses/sd2018/sd2018.html --Ted This message was composed in plain text and may contain plain text formatting of source code, tables, and lists. Reading it in a client that ignores "excess" whitespace characters or line breaks may destroy that formatting, making this message unreadable. Outlook does that by default; learn how to disable the "Auto Remove Line Breaks" ""feature"" at support.microsoft.com

Oct. 16, 2018

Postdoctoral position in circuit modelling at Nottingham, deadline 7th November

by Mark Humphries

A postdoctoral position is available in the lab of Prof Mark Humphries at the University of Nottingham. We seek a postdoctoral researcher to tackle the deep question of how dopamine controls the dynamics of the striatum. As the main target of dopamine in the brain, the striatum bears the brunt of dopamine loss in Parkinson’s disease. Yet how dopamine controls the output of the striatum, and how the loss of dopamine disrupts that output, is unknown. The successful candidate will be responsible for constructing and simulating models of the striatum to investigate how dopamine controls the striatum’s dynamics, and the implications this will have for Parkinson’s disease. The project will build upon the detailed models of the striatum from the Humphries group (e.g. Humphries et al 2009 Neural Networks; 2010, PLoS Computational Biology). This is also a chance to join the newly-created computational neuroscience centre at Nottingham, which includes Profs Mark van Rossum and Stephen Coombes. Find out more about the lab and its interests here: https://www.humphries-lab.org/ The post will be available for 18 months in the first instance. More details, eligibility, and application instructions here: https://www.nottingham.ac.uk/jobs/currentvacancies/ref/SCI353818 Deadline: 7th November 2018 To discuss this or other projects, please contact Mark (mark.humphries(a)nottingham.ac.uk)

Oct. 16, 2018

Fully-funded PhD in computational neuroscience at Nottingham, deadline 31st October

by Mark Humphries

A fully funded PhD position in Computational Neuroscience is available with Prof. Mark Humphries at the School of Psychology, University of Nottingham. Deadline: October 31st Full details and to apply: https://www.nottingham.ac.uk/psychology/news/funded-phd-opportunity-prof-ma… The Humphries’ lab interrogates how the joint activity of many neurons encodes the past, present, and future, in order to guide behaviour. We combine simulations of neural circuits with “neural data science” – the development and use of machine-learning approaches to systems neuroscience data. We are particularly interested in PhD projects on the following research questions: * “Mapping the wires from neural activity”. How to use the next generation of imaging techniques that directly record neuron voltages to accurately infer the wiring between neurons. * “How to write activity into neurons". What features of neural activity should we change with optogenetics in order to test hypotheses about population activity? * “Dynamic control of the striatum in health and disease”. How the influence of the striatal interneurons is controlled by dopamine, and how that influence goes haywire when dopamine is lost in Parkinson’s disease. For a primer on our research, and our recent publications, visit our lab website: /https://www.humphries-lab.org/ To discuss these or other projects, please contact Prof Mark Humphries (mark.humphries(a)nottingham.ac.uk)

Oct. 16, 2018