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Two postdoctoral positions in cellular electrophysiology and neurobiology at SISSA, Italy
by Michele Giugliano Feb. 19, 2020

Feb. 19, 2020

Apologies for cross posting Two postdoctoral positions in cellular electrophysiology and neurobiology ------------------------------------------------------------------------------------------------- Two postdoctoral positions are available immediately at the Neuroscience Area of SISSA - the International School for Advanced Studies, in the lab of Neuronal Dynamics head by Dr. Michele GIUGLIANO. Both positions are funded for up to 38 months each, on a newly funded EC-Horizon 2020 project called "Ionic Neuromodulation For Epilepsy Treatment (IN-FET)". This project combines neurobiology, nanotechnologies, electrochemistry, and electronics together towards a novel breakthrough technology in brain modulation. At SISSA, we aim at experimentally validating novel routes for cellular and microcircuit stimulation or suppression, in collaboration with a consortium of partners which includes IBM Research Zurich, the University of Geneva, the University of Sheffield, and the Inter-university consortium for Nanoelectronics. We thus search for experts in in vitro electrophysiology (substrate-integrated microelectrode arrays) and patch-clamp recordings (dissociated cell cultures, acute and organotypic brain tissue slices) with a strong background in quantitative data analysis and an interest for interdisciplinary research. The deadline for the application is 19/03/2020 and the link to apply is https://pica.cineca.it/sissa/ar-fe-neur-17-2020/ <https://pica.cineca.it/sissa/ar-fe-neur-17-2020/> More information at: https://www.sissa.it/bandi/selezione-pubblica-titoli-colloquio-conferimento… <https://www.sissa.it/bandi/selezione-pubblica-titoli-colloquio-conferimento…> For any scientific information, email to michele.giugliano(a)sissa.it <mailto:michele.giugliano@sissa.it> For any administrative information, email to assegniricerca(a)sissa.it <mailto:assegniricerca@sissa.it>

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Neural coding in high dimensional, nonlinear systems workshop in Paris
by Trang-Anh Nghiem Feb. 19, 2020

Feb. 19, 2020

Dear Colleagues, We are delighted to announce that our workshop on *neural coding in high dimensional, nonlinear systems* will be held on *March 24th-25 2020*. The event is organised by the European Institute for Theoretical Neuroscience (EITN) and will take place at the Institute for Advanced Study (IAS) on the Île Saint-Louis in central Paris. *Conference abstract* In this workshop we address mechanisms by which brains encode information. We will discuss how neurons - leaky, stochastic channels - interact nonlinearly to entrain synchrony and resonance phenomena thereby reducing dimensionality in dynamics of the cell assemblies coding particular representations. From unconscious to conscious brain states, spontaneous neural signals increase in dimensionality. Since neural codes likely lie on low dimensional manifolds, we explore collapses in dimensionality within encoding networks as mechanisms supporting neural information specifically in conscious states. We aim to bring together researchers in neuroscience, mathematics, physics, and computer science to explore substrates promoting self-organization of neural dynamics, toward a robust understanding of neural codes important for reverse engineering next generation biomimetic computing architectures. *Confirmed speakers*- Mallory Carlu (Centre National de la Recherche Scientifique) - Damien Depannemaecker (Centre National de la Recherche Scientifique) - Alain Destexhe (Centre National de la Recherche Scientifique) - Leon Glass (McGill University) - Jennifer Goldman (Centre National de la Recherche Scientifique) - Julie Grollier (Centre National de la Recherche Scientifique/Thales) - Hermann Haken (Universität Stuttgart) - Vincent Hakim (Ecole Normale Supérieure de Paris) - Viktor Jirsa (Aix-Marseille University) - Trang-Anh Nghiem (Ecole Normale Supérieure de Paris) - Maris Ozols (University of Amsterdam) - Wolf Singer (Ernst Strüngmann Institute, Max Planck Society) - David Ruelle (Paris-Saclay University) - Núria Tort-Colet (Centre National de la Recherche Scientifique) - Sacha van Albada (Forschungszentrum Jülich) *Attendance is free but registration is mandatory due to a limited number of seats. To apply for registration, please visit the conference website*: https://neuralcoding.sciencesconf.org/. Looking forward, Best wishes, The organisers: Jennifer S. Goldman, Trang-Anh E. Nghiem, Alain Destexhe, Wolf Singer, with the support of the Paris IAS

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CAMP@Bangalore 2020 Course Announcement
by U.S.Bhalla Feb. 19, 2020

Feb. 19, 2020

Dear Colleagues, We would like to announce CAMP@Bangalore 2020 from 29 June 2020 to 14 July 2020. CAMP (Computational Approaches to Memory and Plasticity at NCBS, Bangalore) is a 16-day summer school where students will be trained in theoretical and computational modeling, pertaining to memory and plasticity in the brain, spanning different scales of space, time and complexity. This flavor of CAMP will focus on — Hippocampus beyond Space, and Dimensionality & Manifolds. The course will have lectures, hands-on tutorials, and project work to launch students into the exciting field of computational neuroscience. The course is supported by the Simons Foundation. Students worldwide are encouraged to apply. Accommodation and food will be free for the selected students. There is no registration fee. Students are advised to obtain independent travel grants. Application deadline: 5 March 2020. Referee letters must reach by 7 March 2020 Speakers: Aaron Batista, University of Pittsburgh, USA Alessandro Treves, SISSA, Italy Collins Assisi, IISER Pune, India Kishore Kuchibhotla, Johns Hopkins University, USA Marianne Fyhn, University of Oslo, Norway Marlene Bartos, University of Freiburg, Germany Sachin Deshmukh, IISc Bangalore, India Srdjan Ostojic, ENS Paris, France Suhita Nadkarni, IISER Pune, India Taro Toyoijumi, RIKEN, Japan Torkel Hafting, University of Oslo, Norway Visit the course website http://camp.ncbs.res.in/ for more details about the course and previous CAMPs. Course Organizers: Arvind Kumar (KTH Stockholm) Rishikesh Narayanan (Indian Institute of Science, Bangalore) Upinder Bhalla (National Centre for Biological Sciences, Bangalore) Best, Organizers CAMP 2020 Course http://camp.ncbs.res.in/

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DENDRITES 2020: Call for Abstracts extended to Feb. 22nd, 2020
by Yiota Poirazi Feb. 19, 2020

Feb. 19, 2020

Dear friends and colleagues, in response to multiple requests, the deadline for abstract submission to DENDRITES 2020 has been extended to February 22nd. Few spots are available for oral presentations by young students/postdocs, to be based on selected abstracts. DENDRITES 2020 EMBO Workshop on Dendritic Anatomy, Molecules and Function Heraklion, Crete, Greece 27-30 June 2020 http://meetings.embo.org/event/20-dendrites We look forward to welcoming you to Heraklion for another exciting meeting on dendrites and beyond! on behalf of the organizers, Yiota Poirazi -------- Panayiota Poirazi, Ph.D. Research Director Institute of Molecular Biology and Biotechnology (IMBB) Foundation of Research and Technology-Hellas (FORTH) Vassilika Vouton, P.O.Box 1385, GR 70013, Heraklion, Crete GREECE Tel: +30 2810 391139 Fax: +30 2810 391101 Εmail: poirazi(a)imbb.forth.gr Lab site: www.dendrites.gr

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Swartz postdoc in theoretical neuroscience at Harvard
by Blum, Kenneth I. Feb. 18, 2020

Feb. 18, 2020

The Swartz Program at Harvard University seeks applicants for a postdoctoral fellow in theoretical and computational neuroscience. Based on a grant from the Swartz Foundation<https://urldefense.proofpoint.com/v2/url?u=http-3A__www.theswartzfoundation…>, a Swartz postdoctoral fellowship is available at Harvard University with a start date in 2020. Postdocs join a vibrant group of experimental and theoretical neuroscientists at Harvard's Center for Brain Science. The Center for Brain Science includes junior and senior faculty doing research on a wide variety of topics, including neural mechanisms of rodent learning, decision-making, and sex-specific and social behaviors; reinforcement learning in rodents and humans; human motor control; behavioral and fMRI studies of human cognition; circuit mechanisms of learning and behavior in worms, larval flies, and larval zebrafish; circuit mechanisms of individual differences in flies and humans; rodent and fly olfaction; inhibitory circuit development; retinal circuits; and large-scale reconstruction of detailed brain circuitry. Interested applicants should immediately send a CV, statement of research interests, and arrange for three letters of reference to be sent to Haim Sompolinsky (haim(a)fiz.huji.ac.il<mailto:haim@fiz.huji.ac.il>), Kenneth Blum (kenneth_blum(a)harvard.edu<mailto:kenneth_blum@harvard.edu>), Sam Gershman (gershman(a)fas.harvard.edu<mailto:gershman@fas.harvard.edu>), or Cengiz Pehlevan (cpehlevan(a)seas.harvard.edu<mailto:cpehlevan@seas.harvard.edu>). Applications should have “Swartz Fellowship” in the subject line. Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

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[meetings] [LM2020] Living Machines 2020 - Second call for papers
by Vicky Vouloutsi Feb. 18, 2020

Feb. 18, 2020

Dear colleagues, Please find below the second call for papers, satellite events, and sponsors for the 9th International Conference on Biomimetic and Biohybrid Systems of Living Machines, 28th-31st of July 2020. Apologies for cross-posting but please share this announcement with your colleagues. Looking forward to seeing you in Freiburg, Germany! -------------------------------------------------------------------------------------------------------------------------- *Second Call for Papers, Satellite Events and Sponsors* *Living Machines. The 9th International Conference on Biomimetic and Biohybrid Systems* * 28 – 31 July 2020* To be hosted at the Botanical Garden of Freiburg and the Cluster of Excellence livMatS at the University of Freiburg, Germany Accepted papers will be published in *Springer Lecturer Notes in Artificial Intelligence* *Submission deadline: March 23, 2020* http://livingmachinesconference.eu/2020 -------------------------------------------------------------------------------------------------------------------------- *ABOUT LIVING MACHINES 2020* The development of future real-world technologies will depend strongly on our understanding and harnessing of the principles underlying living systems and the flow of communication signals between living and artificial systems. *Biomimetics* is the development of novel technologies through the distillation of principles from the study of biological systems. The investigation of biomimetic systems can serve two complementary goals. First, a suitably designed and configured biomimetic artefact can be used to test theories about the natural system of interest. Second, biomimetic technologies can provide useful, elegant and efficient solutions to unsolved challenges in science and engineering. *Biohybrid* systems are formed by combining at least one biological component—an existing living system—and at least one artificial, newly-engineered component. By passing information in one or both directions, such a system forms a new hybrid bio-artificial entity. The theme of the conference also encompasses biomimetic methods for manufacture, repair, and recycling inspired by natural processes such as reproduction, digestion, morphogenesis, and metamorphosis. The following are some examples of “Living Machines” as featured at past conferences: * Biomimetic robots and their component technologies (sensors, actuators, processors) that can intelligently interact with their environments. * Biomimetic computers—neuromimetic emulations of the physiological basis for intelligent behavior. * Active biomimetic materials and structures that self-organize and self-repair or show other bio-inspired functions. * Nature-inspired designs and manufacturing processes. * Biohybrid brain-machine interfaces and neural implants. * Artificial organs and body-parts including sensory organ-chip hybrids and intelligent prostheses. * Organism-level biohybrids such as robot-animal or robot-human systems. *ACTIVITIES* The main conference will take the form of a *three-day single-track oral* and *poster presentation program*, *28th July to 31st July 2020*, and will be hosted at the Botanical Garden of Freiburg by the University of Freiburg, Germany, and the Cluster of Excellence “Living, Adaptive and Energy-autonomous Materials Systems (livMatS)” (www.livmats.uni-freiburg.de<http://www.livmats.uni-freiburg.de/>). The conference program will include *five plenary lectures* from leading international researchers in biomimetic and biohybrid systems, and the demonstrations of state-of-the-art living machine technologies. The full conference will be preceded by up to two days of *Satellite Events* hosted at the University of Freiburg. *SUBMITTING TO LIVING MACHINES 2020* We invite both *full papers* and *extended abstracts* in areas related to the conference themes. All contributions will be refereed and accepted papers will appear in the Living Machines Proceedings, published in the *Springer-Verlag Lecture Notes in Artificial Intelligence*. Full papers (minimum 8 pages, up to 12 pages) are invited from researchers at any stage in their career and should present significant findings and advances in biomimetic or biohybrid research. More preliminary work is better suited for short paper submission (maximum 4 pages, with a maximum of ten references and no more than three self-citations). Full papers will be accepted for either oral presentation (single track) or poster presentation with a short podium preview. Extended abstracts will be accepted for poster presentations only. Authors of the best full papers will be invited to submitted extended versions of their paper for publication in a special issue of the Taylor & Francis journal *Connection Science*. *SATELLITE EVENTS* Active researchers in biomimetic and biohybrid systems are invited to propose topics for full or half-day *tutorials*, *symposia* or *workshops* on related themes to be held on 28. July at the Institute for Biology II/III of the University of Freiburg (http://www.bio.uni-freiburg.de/index-en?set_language=en) Attendance at satellite events will attract a small fee intended to cover the costs of the meeting. There is flexibility about the content, organization, and budgeting for these events. Please contact us if you are interested in organizing a satellite event! *EXPECTED DEADLINES* March 23, 2020: Paper submission deadline May 15, 2020: Notification of acceptance May 25, 2020: Camera-ready copy July 28, 29-31, 2020 Workshops and Conference *SPONSORSHIP* Organizations wishing to sponsor the conference in any way and gain the corresponding benefits by promoting themselves and their products through conference publications, conference events, and conference publicity are encouraged to contact the organizers to discuss the terms of sponsorship and necessary arrangements. We also offer a number of attractive options for potential sponsors. *VENUE* Consistent with the Living Machines’ tradition of choosing historical venues at the crossroads between life and human sciences, this year the conference will take place at the Botanical Garden of Freiburg. Freiburg is considered the gateway to the Black Forest and thanks to its geographical location is blessed with mild weather all year round. The city is over 900 years old and known to be the sunniest city(1,740 hours of sunshine/year) in Germany. Freiburg has a beautiful historical inner city and is home to one of the oldest universities and Botanical Gardens in Germany. The Botanical Garden Freiburg will be celebrating its 400 year anniversary in 2020 and is located in the district Herdern near the Botanical Institute of the University of Freiburg. The Botanical Garden invites visitors to enjoy its wonderful greenery and learn about both plants from all around the world and plant-based biomimetics with its biomimetic educational trail. The trail highlights biomimetic inventions based on plants while providing fascinating insights into underlying biological principles. *CONFERENCE ORGANIZING COMMITTEE* *Thomas Speck* University of Freiburg, Germany (Local Chair) *Paul Verschure* IBEC, BIST, ICREA, CSN Foundation (Co-Chair) *Tony Prescott* University of Sheffield, CSN Foundation (Steering Committee) *Anna Mura* IBEC, BIST Barcelona, CSN Foundation (General Organization) *PROGRAM CHAIR* *Vicky Vouloutsi* IBEC, BIST, Barcelona *COMMUNICATION* *Sonja Seidel* University of Freiburg, Germany *Yulia Sandamirskaya* INI, Zurich Univ. and ETH *WORKSHOPS CHAIR* *Falk Esser* University of Freiburg, Germany *LOCAL ORGANIZERS COMMITTEE* *Thomas Speck* University of Freiburg, Germany *Falk Esser* University of Freiburg, Germany *Sonja Seidel* University of Freiburg, Germany Aquest correu electrònic conté informació confidencial emparada pel secret professional. Qualsevol reproducció, distribució o divulgació del seu contingut estan estrictament prohibides. Si vostè no és el destinatari, li preguem no faci difusió ni copiï el seu contingut i ens ho notifiqui el més aviat possible a l'adreça dataprotection(a)ibecbarcelona.eu Este correo electrónico contiene información confidencial amparada por el secreto profesional. Cualquier reproducción, distribución o divulgación de su contenido están estrictamente prohibidas. Si usted no es el destinatario, le rogamos no difunda ni copie su contenido y nos lo notifique de inmediato a la dirección dataprotection(a)ibecbarcelona.eu This electronic transmission contains confidential information covered by professional secrecy. Any reproduction, distribution or disclosure of its contents is strictly prohibited. If you are not the intended recipient, you are kindly requested not to disseminate nor to copy this transmission and to notify us as soon as possible by email to dataprotection(a)ibecbarcelona.eu .

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PhD Studentship – Modelling cortico-subcortical oscillatory connectivity.
by Dimitris Pinotsis Feb. 18, 2020

Feb. 18, 2020

PhDStudentship – Modelling cortico-subcortical oscillatory connectivity. Applicationsare invited for a 3-year funded PhD studentship in the Wellcome Centre forHuman Neuroimaging (https://www.fil.ion.ucl.ac.uk/) under the supervision ofDr. Vladimir Litvak and Dr. Simon Farmer and in collaboration with theComputational Neuroscience Group (CNS, https://www.upf.edu/web/cns) led byProf. Gustavo Deco, at the Center for Brain and Cognition(https://www.upf.edu/web/cbc), Pompeu Fabra University (Barcelona, Spain). The position is part of the EU-fundedInnovative Training Network euSNN (“European School of Network Neuroscience”)and available, with full-time employment, for a duration of 3 years withimmediate start. TheeuSNN Innovative Training Network integrates 16 leading European groups innetwork neuroscience and 7 companies to train students who want to pursue asuccessful career in the field of network neuroscience. The euSNN trainingprogramme offers a unique combination of experimental, analysis and modellingapproaches. Exploiting intense collaborations between experimental, theoreticaland clinical groups, euSNN links basic research on large-scale brain dynamicswith new pathophysiological approaches and clinical applications. The euSNNnetwork is coordinated by Prof. Dr. Andreas K. Engel. Further information onthe euSNN network can be found at http://eusnn.eu. Project details Deep Brain Stimulation(DBS) is an effective treatment method for a range of neurological andpsychiatric conditions. It involves placing electrodes deep in a patient’sbrain, usually in precisely targeted subcortical nuclei. DBS surgery affords aunique opportunity to study the neural activity of these nuclei via recordingof local electrical signals known as local field potentials (LFP). Our grouppioneered simultaneous recording of subcortical LFP with non-invasive wholebrain imaging using magnetoencephalography (MEG). This makes it possible to mapout cortico-subcortical oscillatory coherent networks which have characteristicfrequencies and cortical topographies for each subcortical target. Over theyears we collected data from several different subcortical nuclei andcharacterised their oscillatory networks. The aim of the proposed project is toestablish a modelling framework which could accommodate these findings and makequantitative predictions for future experiments. This will require extendingexisting models of cortical dynamics and integrating information fromadditional imaging modalities such as functional MRI and Diffusion TensorModelling (DTI). The euSNN training networkoffers exciting and unique opportunities for the student to pursue this projectincluding interactions with top experts in neuroimaging brain modelling andexposure to several different modelling frameworks and approaches that thestudent will have to master and integrate to achieve the project’s goals. Theremight also be opportunities towards the end of the project to test some of thepredictions experimentally. In addition, the student will have a chance to workon secondments with commercial companies on topics relevant to the project. Funding notes The starting date can beany date between being offered the position and 1st October 2020 andthe contract is for 36 months. The studentship includes UK/EU tuition fees anda stipend along with additional funds to cover travel and accommodation duringsecondments and network activities. Overseas fees cannot be covered. Entry requirements Applicants should have an HonoursDegree (minimum 2:1) in a quantitative discipline: Physics/Mathematics/Engineering/Computer science, strong mathematical background and interestin neuroscience. Knowledge of scientific programming languages, particularlyMatlab, background in modelling complex physical systems and a relevant Mastersqualification is desirable. Applicants should be willing to travel to attendthe network activities and spend prolonged periods of time (up to a few monthsat a time and at least 8 months in total) doing secondments outside the UK. Applicantsmust not have been residing in the UK for more than 12 months prior to thestart of the appointment. Deadline 30th April 2020. Shortlisted candidates will beinterviewed in May. How to apply: Applicants should submit 1)a CV, 2) a 1-page statement detailing why you want to do the PhD, motivation,interest and suitability for the project, 3) a copy of your strongest singlepiece of academic work (e.g. thesis, publication), and 4) contact details oftwo referees. Please ensure that each document is clearly labelled with yoursurname. Please send all documents to Kamlyn Ramkissoon k.ramkissoon(a)ucl.ac.ukby 30th April 2020.Interviews will be held in May 2020. Informal enquiries are welcome to Dr Vladimir Litvak (email: v.litvak(a)ucl.ac.uk)

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Postdoctoral position in functional neuroimaging
by Alessandro Gozzi Feb. 18, 2020

Feb. 18, 2020

The Functional Neuroimaging Laboratory (https://www.iit.it/research/lines/functional-neuroimaging) at Istituto Italiano di Tecnologia (IIT) in Rovereto (Italy) is looking for a Postdoctoral scientist interested in studying the neural basis of functional connectivity disruption in autism. Our research is aimed at identifying the general neural and cellular principles governing the assembly of brain connectivity, and its breakdown in developmental disorders such as autism. We address these questions by mapping functional connectivity alterations in people with autism and model organisms harboring autism-associated genetic etiologies. For reference to recent work relevant to this position, please see Gutierrez-Barragan et al., Current Biology (2019) and Bertero et al., Brain (2018). The successful candidate must have a PhD in cognitive neuroscience, physics, neuroinformatics or equivalent, a proven record in the analysis of functional images of the mammalian brain, plus a sound knowledge of signal processing and statistical methods applied to brain imaging. We evaluate candidates that are proactive, highly-motivated, and who are willing to interact with both experimental and computational neuroscientists. The IIT center in Rovereto is actively expanding its infrastructure for systems level neuroscience research, and is inserted both in the vibrant community of the IIT and that of CIMeC (www.cimec.unitn.it) within the University of Trento, which specializes in cognitive neuroscience. Please submit your application, including a detailed CV with a brief research statement, a cover letter and name and contacts of 2 referees, by email to alessandro.gozzi(a)iit.it, quoting "Postdoctoral position in neuroimaging - CB 78211" in the email subject. The first deadline for applications is March 20th, 2020. This position will remain open until filled. Salary will be commensurate with qualifications and experience. Fondazione Istituto Italiano di Tecnologia (http://www.iit.it) is a non-profit institution created with the objective of promoting technological development and higher education in science and technology. Research at IIT is carried out in highly innovative scientific fields with state-of-the-art technology. Istituto Italiano di Tecnologia is an equal opportunity employer that actively seeks diversity in the workforce. Please note that the data that you provide will be used exclusively for the purpose of professional profiles' evaluation and selection, and in order to meet the requirements of Istituto Italiano di Tecnologia. Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security. Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone +39 010 71781 - email: dpo[at]iit.it) Contacts Alessandro Gozzi alessandro.gozzi(a)iit.it<mailto:alessandro.gozzi@iit.it> Twitter: Gozzi_Ale Alessandro Gozzi, PhD Senior Scientist, Group Leader Functional Neuroimaging Laboratory Istituto Italiano di Tecnologia Center for Neuroscience and Cognitive Systems @ UNITN Corso Bettini 31, 38068 Rovereto, Italy Tel: +39 0464 808 701

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Three permanent associate professor positions in data science
by Hans Ekkehard Plesser Feb. 18, 2020

Feb. 18, 2020

The Faculty of Science and Technology at the Norwegian University of Life Sciences is expanding its data science activities in research and education and invites applications for Three permanent associate professor positions in data science with focus on * Machine learning for the 21st century (https://www.jobbnorge.no/en/available-jobs/job/183310/associate-professor-i…) * Data management for a data science world (https://www.jobbnorge.no/en/available-jobs/job/183306/associate-professor-i…) * Value-oriented deployment of data science (https://www.jobbnorge.no/en/available-jobs/job/183315/associate-professor-i…) Closing date for all positions is 22 March 2020. For details and to apply, please see the full announcements for the positions linked above. Background information about us, our programs and our expectations is available in https://arken.nmbu.no/~plesser/NMBU_ThreeAssocProfsDataScience_AdditionaInf… Best regards, Hans Ekkehard Plesser -- Prof. Dr. Hans Ekkehard Plesser Head, Data Science Section Faculty of Science and Technology Norwegian University of Life Sciences PO Box 5003, 1432 Aas, Norway Phone +47 6723 1560 Email hans.ekkehard.plesser(a)nmbu.no<mailto:hans.ekkehard.plesser@nmbu.no> Home http://arken.nmbu.no/~plesser

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Grandmother cells a failed concept? Or is Barlow right that grandmother cells exist and “can now be recorded from and studied reliably?"
by Asim Roy Feb. 16, 2020

Feb. 16, 2020

Ann-Sophie Barwich recently published an article in Frontiers in Neuroscience titled “The Value of Failure in Science: The Story of Grandmother Cells in Neuroscience” (https://www.frontiersin.org/articles/10.3389/fnins.2019.01121/full) where she argues for the need for failure analysis in science and, in the context of neuroscience, analyzed the grandmother cell concept as a failed one. Although I was one of the reviewers who endorsed the article for publication (publication of alternative viewpoints is essential in science), I felt that Barwich’s arguments against grandmother cells were deeply flawed. I point out these flaws in a Commentary in Frontiers in Neuroscience: “Commentary: The Value of Failure in Science: The Story of Grandmother Cells in Neuroscience:” https://www.frontiersin.org/articles/10.3389/fnins.2020.00059/full I think Reddy and Thorpe’s 2014 article clears the confusion about concept cells. With Reddy and Thorpe’s characterization of concept cells, one would find no difference between concept cells and grandmother cells. And that’s essentially what I have done in the Commentary – show that concept cells and grandmother cells have identical properties. I also point out in the Commentary that it’s a false claim by Barwich (and in other prior articles that Barwich references) that concept cells can be part of a sparse population coding scheme. Given that concept cells have “meaning” on a stand-alone basis, they can’t be part of any population coding scheme. And it’s also a false claim in Barwich that grandmother cells do not use associative learning, because grandmother cells have always been characterized as “multimodal” going all the way back to Gross (2002). In addition, the neurophysiological evidence on multisensory neurons clearly point to a single-cell based abstract cognitive system in the brain, as claimed by Roy (2017). Overall, concept cell findings confirm the prediction of Barlow (2009)<https://www.frontiersin.org/articles/10.3389/fnins.2020.00059/full#B1> that grandmother cells exist and “can now be recorded from and studied reliably.” YOU CAN EMAIL ME IF YOU WANT TO JOIN A DISCUSSION GROUP ON THIS TOPIC. Barlow, H. B. (2009). “Grandmother cells, symmetry, and invariance: how the term arose and what the facts suggest,” in The Cognitive Neurosciences, 4th Edn., ed M. Gazzaniga (Cambridge, MA: MIT Press), 309–320. Reddy, L., and Thorpe, S. J. (2014). Concept cells through associative learning of high-level representations. Neuron 84, 248–251. doi: 10.1016/j.neuron.2014.10.004 Roy, A. (2017). The theory of localist representation and of a purely abstract cognitive system: the evidence from cortical columns, category cells, and multisensory neurons. Front. Psychol. 8:186. doi: 10.3389/fpsyg.2017.00186

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