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Contrat post-doctorant 2018-2020 - Laboratoire FrontLAB, Institut du Cerveau et de la Moelle Epinière (ICM), PARIS (FR)
by Bénédicte BATRANCOURT Aug. 16, 2018

Aug. 16, 2018

*Contrat post-doctoral 2018-2020* Laboratoire FrontLAB, Institut du Cerveau et de la Moelle Epinière (ICM), PARIS Inserm, U 1127, CNRS, UMR 7225, Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127 https://icm-institute.org/fr/ L’Institut du Cerveau et de la Moelle épinière (ICM) est un centre de recherche de dimension internationale, innovant dans sa conception comme dans son organisation. En réunissant en un même lieu malades, médecins et chercheurs, l’objectif est de permettre la mise au point rapide de traitements pour les lésions du système nerveux afin de les appliquer aux patients dans les meilleurs délais. D’un point de vue scientifique, les équipes de recherche sont indépendantes, mais alliées entre elles par des Programmes Transversaux de Recherche favorisant la mutualisation des compétences. La recherche se décline selon trois modèles : la recherche fondamentale orientée vers les domaines fondamentaux d’une discipline, la recherche clinique dans laquelle le sujet participe à des protocoles pour améliorer la connaissance d’une pathologie ou d’une thérapeutique et la recherche translationnelle qui permet aux patients de bénéficier plus rapidement des innovations diagnostiques et thérapeutiques. La recherche à l’ICM couvre 4 domaines scientifiques majeurs : Neurosciences Moléculaires et Cellulaires, Neurophysiologie intégrée, Neurosciences Cognitives, Neurosciences Cliniques et Translationnelles. Dans notre équipe FRONTlab (Richard LEVY, Bruno DUBOIS), nous travaillons sur les fonctions mentales élaborées par les lobes frontaux. L’un des enjeux majeurs des neurosciences est de connaître en profondeur les fonctions frontales afin de *comprendre comment sont élaborés et contrôlés nos comportements les plus complexes* (prise de décision, planification raisonnement, créativité, jugement moral, interactions sociales…). Une connaissance approfondie des lobes frontaux est aussi indispensable pour mieux traiter les nombreuses maladies neurologiques et psychiatriques s’accompagnant d’une atteinte des lobes frontaux (maladie d’Alzheimer, AVC, traumatismes crâniens, dépression, schizophrénie…). Nos objectifs sont de mieux cerner l’implication des lobes frontaux dans le comportement humain et les fonctions intellectuelles les plus élaborées, et de transférer les connaissances acquises vers la pratique médicale. Nous proposons un contrat de postdoctorant de 2 ans afin de participer au développement du projet ECOCAPTURE, permettant d’évaluer l’apathie de façon quantitative et objective, par l’observation du sujet en condition proche de la vie réelle. L’étude ECOCAPTURE se déroule dans la plate-forme de recherche de psychologie expérimentale de l'ICM (PRISME) qui est consacrée à l'exploration fonctionnelle du comportement humain dans des situations écologiques. L’étude ECOCAPTURE a débuté en septembre 2017, et porte sur 75 patients (Démence Fronto-Temporale, Parkinson, Dépression) et 60 volontaires sains. A ce jour 16 participants ont été inclus (8 patients et 8 volontaires sains). Dans cette étude et la phase dite de laboratoire, *l’apathie est évaluée en condition observationnelle* grâce à un système qui enregistre le comportement du sujet à l’aide d’un système à base de vidéo et de capteurs, durant une session expérimentale de 45 mn « proche de la vie réelle » qui se déroule dans une salle d’attente, selon un scénario contrôlé. L’objectif principal de l’étude ECOCAPTURE est de montrer que l’outil ECOCAPTURE basé sur des enregistrements vidéo et des capteurs d’activité et de mouvements, possède une valeur d’outil diagnostique de l’apathie. La méthode générale concerne en l’extraction de métriques comportementales à partir des données vidéo et des données extraites d’un accéléromètre 3D afin de différencier le comportement des patients de celui des sujets volontaires sains. L’étude ECOCAPTURE est la première étape d'un programme en trois phases visant à mieux évaluer l'apathie en situation « proche de la vie réelle » et à proposer de nouveaux traitements. La première phase dite « de laboratoire » a pour objectif la mise en œuvre d’un outil diagnostic de l'apathie produisant une « signature simple du comportement dirigé vers un but » ou « signature comportementale de l’apathie » permettant d'évaluer l'apathie, en situation de vie quotidienne, de façon objective (un marqueur d'apathie). Nous espérons que la création et la validation de cet outil ECOCAPTURE rendra possible dans une deuxième phase, son utilisation en clinique ainsi qu’une évaluation au domicile *ECOCAPTURE@home* avec un système de capteurs embarqués : un « holter d'apathie ». Une troisième phase visera à proposer un traitement des conséquences de l'apathie dans la vie quotidienne. L’objectif de ce contrat postdoctoral est de développer la deuxième phase : *ECOCAPTURE@home*. Nous recherchons un candidat titulaire d’un doctorat en neurosciences, sciences cognitives ou en bioinformatique, de formation : psychologue, neuropsychologue, neurologue, psychiatre, éthologue ou ingénieur biomédical. Le candidat devra posséder plusieurs compétences parmi la liste suivante : neuropsychologie, éthologie, mesure du comportement, instruments neuropsychologiques, qualités psychométriques d’un outil d’évaluation, capteurs et actigraphie, statistiques, fusion de données, classification. Une bonne connaissance de la langue française est indispensable afin de permettre les interactions avec les patients et leurs aidants. Ce contrat permettra à un chercheur motivé de participer à un projet multidisciplinaire et très original, de collaborer avec des chercheurs de disciplines diverses, de bénéficier d’un environnement scientifique international et stimulant, et de participer à la vie de l’équipe FrontLAB constituée d’un groupe de 12 PI chacun responsable d’un projet dédié à la compréhension du lobe frontal, et accueillant chaque année de nombreux étudiants. *La rémunération sera établie en fonction du barème de rémunération des contractuels Inserm* Merci d’envoyer votre CV avec une lettre de motivation et les noms et emails de deux personnes de référence à Bénédicte BATRANCOURT ( benedicte.batrancourt(a)upmc.fr) avant le 30 septembre 2018. Bénédicte Batrancourt ICM, UPMC, INSERM UMR_S 1127, CNRS UMR 7225 Hôpital Pitié-Salpêtrière 47 Boulevard de l’Hôpital F-75651 PARIS Cedex 13 Tel : 01 57 27 41 59 Tel : 06 60 44 79 79 benedicte.batrancourt(a)upmc.fr http://icm-institute.org ----------------------------------- Afin de contribuer au respect de l'environnement, merci de n'imprimer ce mail qu'en cas de nécessité.

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Up to 8 PhD fellowships in Cognitive Neuroscience at SISSA, Trieste, Italy
by Alessandro Treves Aug. 16, 2018

Aug. 16, 2018

SISSA is an elite postgraduate research institution, focused on Maths, Physics and Neuroscience. It operates in English: many among its students and faculty are not Italian. Campus above Trieste, overlooking the Gulf. Research approaches in the CNS PhD https://phdcns.sissa.it/ span the range from cognitive psychology and imaging in humans to behavioural neuroscience and multiple single-unit recording in rats, mathematical and computational modeling; with research groups led by Domenica Bueti, Davide Crepaldi, Mathew Diamond, Chris Mathys, Raffaella Rumiati, Alessandro Treves and Davide Zoccolan. Allied approaches are pursued in other SISSA PhDs. All admitted students receive a 4-year fellowship and engage full-time in research based in Trieste, with limited coursework in the first few months, talks and seminars throughout the year and a TEX event in the summer, see https://indico.sissa.it/event/26/ First deadline for EU candidates: March 2, 2018, for nonEU: March 31, 2018 -- Alessandro Treves http://people.sissa.it/~ale/limbo.html SISSA - Cognitive Neuroscience, via Bonomea 265, 34136 Trieste, Italy +39-040-3787623 Ambassador (BlaBlaCar) +39-349-2504602

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Save the date ICTALS2019 (IWSP9), Exeter, UK, September 2nd – 5th 2019
by Goodfellow, Marc Aug. 15, 2018

Aug. 15, 2018

Dear All, The International Conference for Technology and AnaLysis of Seizures, 2019 (ICTALS2019) will take place at the University of Exeter, September 2nd – 5th 2019. The goal of this conference is to bring together neurologists, neuroscientists, researchers from quantitative disciplines and people with lived experience of epilepsy in order to work as a community to advance our understanding of epilepsy and develop practical ways to improve diagnosis and treatment. This is the second ICTALS conference, which is an evolution of the previous International Workshop on Seizure Prediction (IWSP) series. The theme for this year’s conference will be: “The Epilepsy Journey: from first seizure to treatment and beyond”. We will emphasise how advances in our understanding of the dynamics of brain networks can be used to make a difference to people with epilepsy at all points of their journey: from elucidating the causes of the first seizure to diagnosing epilepsy, understanding how ictogenic networks give rise to recurrent seizures and how this insight can inform personalised treatment. To encourage this focus on translatable output of research we will seek to include all relevant communities. In addition to focussing on current scientific, clinical and technological advances, we will take steps to increase accessibility for people with lived experience of epilepsy. We have begun to create a webpage for the conference, which we will populate with further information in due course. You can find this at: http://exeter.ac.uk/ictals2019 In the mean time, please save the date above in your diary and we will follow up with further information, including registration and programs over the next few months. Best wishes Marc Goodfellow (on behalf of the local organising committee). https://emps.exeter.ac.uk/mathematics/staff/mg401

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MRC Skills Development Fellowships at the University of Exeter
by Purcell, Sarah Aug. 15, 2018

Aug. 15, 2018

Dear Colleagues, The University of Exeter<http://www.exeter.ac.uk/> is delighted to be partnering with the Medical Research Council<https://mrc.ukri.org/> (MRC) to offer exceptional candidates the opportunity to hold a 3 year Skills Development Fellowship, commencing between November 2018 and March 2019. MRC Skills Development Fellowships are prestigious personal awards, aimed at exceptional early career researchers with a strong background in mathematical, statistical, computational or biophysical modelling and analysis, or for more advanced researchers from a biomedical or clinical background who are seeking to develop strong quantitative skills. The University of Exeter has a wide variety of opportunities to develop these quantitative skills in the context of neuroscience and neurology, endocrinology and metabolism, and primary care population and health services research. Successful applicants will be housed within the brand new £52M Living Systems Institute<https://www.exeter.ac.uk/livingsystems/> where they will be co-located with 8 other MRC Fellowship holders. They will receive 3 years of funding with substantial budgets for travel, skills development and consumables as determined by their project needs. As part of the Fellowship candidates will also have the opportunity to spend up to a year in an internationally leading second research centre. Additionally, candidates will receive a £5,000 career development budget from the University of Exeter. Full details of this opportunity are available from www.exetermrcsdf.ac.uk<http://www.exetermrcsdf.ac.uk/> and in the information video<https://youtu.be/LKgl1WqiRgU>. Applications are now open with a closing date of 13th September 2018. Please do share these details with any potentially interested parties.

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Funded postdoc positions: Synaptic and network mechanisms of visual perception
by Haider, Bilal Aug. 14, 2018

Aug. 14, 2018

The Haider Lab in the Dept. of Biomedical Engineering (BME) at Georgia Tech & Emory University seeks highly motivated and skilled postdoctoral fellows for a 3-5 year NIH funded project examining synaptic and network mechanisms supporting sensory perception. The position is available immediately and conforms to NIH standards for salary and benefits. The project offers significant opportunity to use cutting-edge research techniques in vivo during visual perception. These include 1) neural population recording with high-density silicon electrodes, 2) optogenetic circuit manipulation, and 3) whole-cell patch-clamp recording during behavior. The ideal candidate has expertise in patch clamp or multi-electrode electrophysiology in vitro or in vivo, and quantitative skill in data acquisition and analysis (preferably with MATLAB). Candidates should have excellent written and verbal communication skills, an inquisitive mindset, and enthusiasm to work in a multi-disciplinary team. The position is funded for up to 5 years, pending satisfactory performance upon annual review. We are enthusiastic to form a diverse, international research group. All candidates will be mentored for independent career development. There is a strong, multidisciplinary concentration of labs focusing on Neuroscience at GT and at Emory. Atlanta is vibrant, green, diverse, and one of the most affordable and livable major cities of the US. Applications should include a CV, a brief statement of research goals, expected date of availability, and names and contact information of three references. Please email materials to bilal.haider(a)bme.gatech.edu Further information and recent lab publications can be found at haider.gatech.edu Bilal Haider, Ph.D. Assistant Professor Coulter Dept. of Biomedical Engineering Georgia Tech & Emory University 313 Ferst Drive, Suite 3104 Atlanta, GA 30332 tel: +1 404 385 4935 fax: +1 404 385 5044 site: haider.gatech.edu<http://haider.gatech.edu/> twitter: @haiderlab<https://twitter.com/haiderlab>

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Postdoctoral Research Fellow roles - EPSRC Centre for Predictive Modelling in Healthcare, University of Exeter
by Purcell, Sarah Aug. 13, 2018

Aug. 13, 2018

2 Postdoctoral Research Fellow roles - EPSRC Centre for Predictive Modelling in Healthcare University of Exeter, UK Two Research Fellows are required to support the EPSRC Centre for Predictive Modelling in Healthcare<http://emps.exeter.ac.uk/mathematics/research/pmh/> (CPMH). The roles are available from 01 October 2018, or a mutually agreeable date soon thereafter, for a period of up to 24 months. The CPMH is a £2M award which brings together outstanding scientists from mathematics, statistics, computer science and our medical school. With an additional £7M in research funding, the interface between mathematics, computer science and healthcare is one of the most rapidly expanding areas within the University. The Centre forms part of the Quantitative Biology and Medicine Initiative, which currently consists of 15 PDRAs, 9 fellowship holders, and 10 PhD students. The successful candidates are expected to focus on one of the following areas, depending on their interests and background: (a) Transient dynamics of networks with multiple time scales: there are significant mathematical challenges from disease modelling that require the development of new techniques to understand transient behaviour in multiple timescale systems, especially for systems where there is not a simple factorization into fast and slow subsystems. (b) Numerical investigation of models of cardiac diseases: involving multi-scale excitable and transient dynamics, with a focus on re-entrant arrhythmias specifically concerning development and improvements of antiarrhythmia pacing, low-voltage defibrillation and catheter ablation. [In partnership with cardiologists at the RD&E Hospital, Exeter]. (c) Mathematical modelling and analysis of EEG in dementia: EEG analysis has shown promise in differentiating people with dementia from healthy older adults, and therefore could provide indications for early diagnosis. We will use mathematical models to better understand why differences in EEG occur and combine models and analysis to build improved diagnostic markers. [In partnership with colleagues in Bath, Bristol & Reading]. (d) Mathematical modelling and analysis of polygenic disease: conditions such as diabetes and dementia depend on the simultaneous presence of several genes; they are not inherited as simply as single-gene diseases and therefore require the development of new mathematical approaches to improve diagnosis via e.g. the interpretation and uncertainty quantification of proportions of patients in large data sets (e.g. UK Biobank) using genetic risk scores. [In partnership with diabetologists and neurologists from the Medical School]. For full details please see the job advert<https://www.jobs.ac.uk/job/BLL261/postdoctoral-research-fellow/>. Application deadline: 20 August 2018. For further information please contact Centre Manager Sarah Purcell, email S.Purcell(a)exeter.ac.uk<mailto:S.Purcell@exeter.ac.uk> or telephone 01392 726447.

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PhD deeplearning in neuroimaging - Amsterdam
by Rajat Thomas Aug. 10, 2018

Aug. 10, 2018

PhD student “Deep learning analysis of neuroimaging data” The job Amsterdam UMC (University of Amsterdam) has a vacancy for a PhD student. The aim of the project is to develop deep neural network (DNN) analysis of neuroimaging data to enable neuroimaging biomarker development. Neuroimaging data consist of thousands of features but the training of DNNs is typically hampered by limited samples. You will use large existing datasets (>10.000 subjects) for the development of DNN analysis and test the resulting models in smaller samples to develop neuroimaging biomarkers for psychiatric disorders. Our department The project is a collaboration with Phillips Research and funded by a public-private partnership grant from the Netherlands Organisation for Scientific Research (NWO). You will closely collaborate with experts in DNN and neuroimaging data analysis from Philips. The project is embedded within the Department of Psychiatry of the Amsterdam UMC, and you will be supervised by Dr. Rajat Thomas (deep learning) and Prof. Guido van Wingen (neuroimaging). Your experience We are looking for a highly talented and dedicated PhD student with a (nearly completed) Master’s degree in a computer science, artificial intelligence, bioinformatics, mathematics, statistics, engineering, or related discipline. You have a strong background in mathematics, statistics, and programming, preferably in one of the major frameworks for deep learning like TensorFlow, Pytorch and/or Keras, and preferably have experience with medical image analysis. You have good communicative skills and are well able to work independently as well as in a team. You are proficient in English in speech and writing. Dutch is a plus but not required. Our offer We offer a challenging research project and excellent resources for the duration of 4 years. The starting date is preferably around December 2018. Compensation is according to the collective agreement (CAO-UMC), and amounts from EUR 2.279,- gross per month in the first year to EUR 2.919,- in the fourth year. You will be employed by AMC Medical Research BV. Your application For more information, please contact Dr. Rajat Thomas (r.m.thomas(a)amc.nl) or Prof. Guido van Wingen (g.a.vanwingen(a)amc.nl) Please apply online before September 8 at https://werkenbijamc.nl/vacatures/phd-student-deep-learning-analysis-of-neu…

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Postdoc deeplearning in medical imaging - Amsterdam
by Rajat Thomas Aug. 10, 2018

Aug. 10, 2018

Postdoctoral / Ph.D. researcher “Deep learning analysis of neuroimaging data” The job Amsterdam UMC (University of Amsterdam) has a vacancy for a postdoctoral researcher. The aim of the project is to develop deep neural network (DNN) analysis of neuroimaging data to enable neuroimaging biomarker development. Neuroimaging data consist of thousands of features but the training of DNNs is typically hampered by limited samples. You will use large existing datasets (>10.000 subjects) for the development of DNN analysis and test the resulting models in smaller samples to develop neuroimaging biomarkers for psychiatric disorders. Our department The project is a collaboration with Phillips Research and funded by a public-private partnership grant from the Netherlands Organisation for Scientific Research (NWO). You will closely collaborate with experts in DNN and neuroimaging data analysis from Philips. The project is embedded within the Department of Psychiatry of the Amsterdam UMC, and you will be supervised by Dr. Rajat Thomas (deep learning) and Prof. Guido van Wingen (neuroimaging). Your experience We are looking for a postdoctoral fellow with a (nearly completed) PhD in computer science, artificial intelligence, bioinformatics, mathematics, statistics, engineering, or related discipline. You have a strong background in mathematics, statistics, and programming in one of the major frameworks for deep learning like TensorFlow, Pytorch and/or Keras, and preferably have experience with medical image analysis. You have excellent communicative skills in written and spoken English (Dutch is a plus but not required) and are well able to work independently as well as in a team. You have an interest in neuroscience and developing biomedical applications, and as postdoctoral researcher will assist in the supervision of junior researchers. Our offer We offer a challenging research project and excellent resources for the duration of 1 year with a possible extension of 2 years. The starting date is preferably around December 2018. Compensation is according to the collective agreement (CAO-UMC), depending on education and experience. You will be employed by AMC Medical Research BV. Your application For more information, please contact Dr. Rajat Thomas (r.m.thomas(a)amc.nl) or Prof. Guido van Wingen (g.a.vanwingen(a)amc.nl) Please apply online at https://werkenbijamc.nl/vacatures/postdoctoral-researcher-deep-learning-ana…

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ESI SyNC Conference 2018 - Integrative Mechanisms of Cognitive Neuroscience | DEADLINE APPROACHING
by André Castro Aug. 9, 2018

Aug. 9, 2018

Dear all, this is a kind reminder that ESI Sync 2018 is approaching. The registration deadline is 15th August and only a limited number of places are available. This year’s theme is "Integrative Mechanisms in Cognitive Neuroscience: Crossroads to the Brain”. The conference will begin in the morning of 30th August and end in the evening of 31st August 2018 at the Ernst Strüngmann Institute in Frankfurt, Germany. Our confirmed invited speakers are the following: - David Melcher (University of Trento, Italy) -- "Temporal rhythms of visual perception" - Dimitri Kullmann (UCL, UK) -- "Hippocampal gamma oscillations: dynamical properties and closed-loop manipulation" - Matteo Carandini (UCL, UK) -- "Local and global neural correlates of vision, action, and reward" - Biyu He (NYU, US) -- ''Large-scale brain dynamics underlying visual perceptual awareness'' - Tobias Donner (UKE, Germany) -- tba - Wim Vanduffel (KU Leuven, Belgium) -- "Optogenetic interrogation of the attention network in primates" - Anitha Pasupathy (University of Washington, US) -- "Encoding things and stuff: multiplexed form and texture signals in primate V4" - Floris de Lange (Radboud University, Netherlands) -- "How do prior expectations influence sensory computations?" - Hannah Monyer (Heidelberg University, Germany) -- ''GABAergic neurons – the cellular substrate for local and long-range synchrony'' - James Bisley (UCLA, US) -- ''The complementary roles of areas LIP and FEF in guiding eye movements'' This year we have the pleasure to announce as our special guest the choreographer Ildikó Tóth! In order to register, please fill out the registration form (that can be found at http://www.esi-frankfurt.de/registration/ ) and email it to events(a)esi-frankfurt.de. Please see our [website](http://www.esi-frankfurt.de/esisync/esisync-home/) for more details and updates on the programme. Organising Committee: Wolf Singer Pascal Fries André Castro Tommaso Tosato Ana Broggini Miriam Mueller Renata Vajda

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Final call and reminder - workshop on Computational Neuroscience and Robotics: University of York, 3-5 Sep 2018.
by David Halliday Aug. 8, 2018

Aug. 8, 2018

The SPANNER workshop on Astrocyte-Neuron interactions, Spiking Neural Networks and Autonomous robotics is still accepting applications to attend. Due to sponsorship we can offer free registration, including meals at this 2.5 day workshop. We have invited speakers from USA, EU and UK. We are still accepting abstracts for contributed talks. Overnight accommodation will be provided for PhD students and early career researchers and PhD student travel bursaries are available. Up to date information is on the web site: https://www.york.ac.uk/spanner-workshop We warmly invite you to the historic city of York next month.

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