November 2025 - Comp-neuro - lists.cnsorg.org

Postdoc positions in nanoscale modeling of neurons, synapses or astrocytes
by Erik De Schutter Nov. 4, 2025

Nov. 4, 2025

The Computational Neuroscience unit (https://www.oist.jp/research/research-units/cnu) at the Okinawa Institute of Science and Technology has openings for postdoctoral researchers interested in nanoscale computational neuroscience modeling. Initial duration is two years with option to extend. We have been spearheading the development of efficient computational tools to simulate electrophysiological, molecular and cell biology processes in neurons at the nanoscale (STEPS project http://steps.sourceforge.net) Examples are detailed simulations of the molecular control of vesicle pools and their release in presynaptic terminals (Science Advances 2025) and of how morphology affects calcium transients in perisynaptic astrocytic processes. We make use of recent experimental data like single cell proteomics and super-resolution imaging of live cells. The modeling technology allows for simulation of complete neurons with their spines. We are looking for postdocs interested in pursuing questions about the function of cerebellar or hippocampal neurons, synapses or astrocytes that require nanoscale simulation. Competences: Experience in computational modeling with a recent PhD in a relevant discipline such as computational biology, neuroscience, molecular biology, biophysics or biochemistry. Experience in programming in Python. Fluent English conversation and writing skills. Benefits / Offer: A seniority-based salary and relocation package are offered. Standard medical insurance and housing allowance are included. This an ideal position to gain experience in a prominent computational neuroscience lab and take part in our international collaborations. Please contact Prof. Erik De Schutter (erik(a)oist.jp) for inquiries.

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World wide VVTNS series (6th season): Wednesday, November 5, 2025, at 11:00 am ET - Georges Debrégeas CNRS, Paris
by David Hansel Nov. 2, 2025

Nov. 2, 2025

[image: VVTNS.png] https://www.wwtns.online <https://streaklinks.com/A9c7PbbpKY7PxB6PaAJWGD3-/https%3A%2F%2Fwww.wwtns.on…> - on twitter: wwtns@TheoreticalWide You are cordially invited to the lecture Georges Debrégeas CNRS, Paris on the topic of Latent-aligned generative models uncover shared structure in spontaneous whole-brain dynamics? The lecture will be held on zoom on Wednesday, November 5, 2025, at *11:00 am ET * > To receive the link: https://www.wwtns.online/register-page > *Abstract: *Assessing how brain activity generalizes across individuals is a central challenge in experimental neuroscience. Traditional task- or stimulus-driven approaches align data through trial averaging and anatomical registration, but these methods fail for spontaneous activity, where no shared temporal reference exists. In this talk, I will introduce a statistical framework, called latent-aligned Restricted Boltzmann Machines, to build a common representational space from whole-brain recordings of spontaneous activity in multiple zebrafish larvae. This shared latent space, composed of spatially localized co-activation motifs or cell assemblies, allows bidirectional mapping of brain states: activity patterns from one fish can be encoded and decoded into another. The translated activity patterns retain their original spatial structure and show high plausibility within the recipient brain. We further use this shared space to segment spontaneous activity into discrete brain states and we quantify their Markovian transition statistics. Remarkably, these state-to-state dynamics are stereotyped across individuals, suggesting that spontaneous activity reflects intrinsic computational priors of neural processing. Together, these results demonstrate how probabilistic generative modeling can bridge individual variability and reveal conserved organizational principles of vertebrate brains. *About VVTNS : Launched as the World Wide Theoretical Neuroscience Seminar (WWTNS) in November 2020 and renamed in homage to Carl van Vreeswijk in Memoriam (April 20, 2022), Speakers have the occasion to talk about theoretical aspects of their work which cannot be discussed in a setting where the majority of the audience consists of experimentalists. The seminars, **held on Wednesdays at 11 am ET,** are 45-50 min long followed by a discussion. The talks are recorded with authorization of the speaker and are available to everybody on our YouTube channel.*

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Call for Papers: "Spiking Neural Networks at Scale" in Frontiers in Neuroscience
by Wei Fang Nov. 2, 2025

Nov. 2, 2025

Dear colleagues: I am glad to tell you that the following research topic is now open for submissions in /Frontiers in Neuroscience/: Spiking Neural Networks at Scale: Learning Algorithms, Architectures, and Real-World Applications Refer to this link for more details: https://www.frontiersin.org/research-topics/74585/spiking-neural-networks-a… Please feel free to submit your article by 24 Dec 2025. -- ----------------------- Wei Fang Postdoc, Electrical & Computer Engineering Yale University, USA

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