State of the Brain - Keystone Symposium Scientific Organizers: Terrence J. Sejnowski and Sten Grillner May 22-26, 2016 Alpbach Congress Centrum, Alpbach, Austria Recent years have seen rapid advances in our understanding of brain biology, driven in part by the development of novel technologies for studying neural networks. Consequently, major national research programs in the EU and US have been launched that will bring together teams of neuroscientists and engineers with the aim of achieving a major advance in understanding brain function and dysfunction. The challenge is to map the circuits of the brain, measure the fluctuating patterns of electrical and chemical activity flowing within those circuits and understand how they give rise to cognitive and behavioral capabilities. This Keystone Symposia conference brings together investigators from around the world to share their discoveries and to plan future projects in this exciting new era for brain research. Conference Program http://www.keystonesymposia.org/index.cfm?e=Web.Meeting.Program&meetingid=1425&subTab=program Registration http://www.keystonesymposia.org/index.cfm?e=Web.Meeting.Registration&meetingid=1425&siteid=51&meetingyear=2016&subTab=reg Early Registration discount deadline: March 22, 2016 MONDAY, MAY 23 08:30 Welcome and Keynote Address Cori Bargmann, Rockefeller University, USA Understanding Brain Function and Dysfunction 09:30 International Brain Programs Henry Markram, EPFL SV BMI LNMC, Switzerland The EU Human Brain Project Walter J. Koroshetz, National Institute of Neurological Disorders and Stroke, NIH, USA The US BRAIN Initiative Mu-ming Poo, Institute of Neuroscience, CAS, China China Brain Project and Non-human Primate Research Christof Koch, Allen Institute for Brain Science, USA Project MindScope - Big Science, Team Science, Open Science to Understand Mouse Cortex 15:30 Panel 1: Coordinating International Programs Chair: Terrence J. Sejnowski, The Salk Institute, USA Cornelia (Cori) Bargmann, Rockefeller University, USA Henry Markram, EPFL SV BMI LNMC, Switzerland Walter J. Koroshetz, National Institute of Neurological Disorders and Stroke, NIH, USA Mu-ming Poo, Institute of Neuroscience, CAS, China Christof Koch, Allen Institute for Brain Science, USA Thomas Skordas, European Commission, Belgium 17:00 Discovering Diversity: Identifying Cell Types in the Brain Botond Roska, Friedrich Miescher Institute, Switzerland Cell Types and Circuits in the Visual System Hongkui Zeng, Allen Institute for Brain Science, USA Genetic Approaches to Brain Circuit Mapping and Cell Type Characterization TUESDAY, MAY 24 08:30 The Brain in Action: Large-Scale Monitoring and Manipulating Neurons Karl Deisseroth, Stanford University, USA Optogenetic Approaches to Neural Circuits David W. Tank, Princeton University, USA Recording Activity from Internal Brain States Mark J. Schnitzer, Stanford University, USA Reading Neural Codes from a Thousand Neurons in Freely Behaving Mice Susumu Tonegawa, Massachusetts Institute of Technology and RIKEN Brain Science Institute, USA Monitoring and Engineering Memory Engram Cells and their Circuits 15:30 Panel 2: Bridging the Gap between Circuits and Behavior Chair: David W. Tank, Princeton University, USA Karl Deisseroth, Stanford University, USA Mark J. Schnitzer, Stanford University, USA Susumu Tonegawa, Massachusetts Institute of Technology and RIKEN Brain Science Institute, USA Winfried Denk, Max Planck Institute of Neurobiology, Germany R. Clay Reid, Allen Institute for Brain Science, USA 17:00 Maps in the Brain: Generating Multi-Scale Neural Circuits Winfried Denk, Max Planck Institute of Neurobiology, Germany Revealing the Core Circuitry in Brains R. Clay Reid, Allen Institute for Brain Science, USA Integrating Circuits, Recordings and Behavior Terrence J. Sejnowski, The Salk Institute, USA Global Traveling Waves in Human Cortex WEDNESDAY, MAY 25 08:30 Advancing Human Neuroscience: Understanding Brain Function and Dysfunction John Donoghue, Wyss Center for Bio- and Neuro-Engineering, Switzerland Brain Computer Interfaces Helen S. Mayberg, Emory University, USA Iterative Strategies to Refine and Optimize DBS for Depression Patricia K. Kuhl, University of Washington, USA What Can Babies' Brains Tell Us About What it Means to be Human? 15:30 Panel 3: What are the Prospects for Helping Humans with Brain Disorders? Chair: John Donoghue, Wyss Center for Bio- and Neuro-Engineering, Switzerland Helen S. Mayberg, Emory University, USA Patricia K. Kuhl, University of Washington, USA Emery N. Brown, MIT-Harvard Division of Health Sciences and Technology, USA Botond Roska, Friedrich Miescher Institute, Switzerland 17:00 Discovering Principles: Theory, Models, Computation and Statistics Emery N. Brown, MIT-Harvard Division of Health Sciences and Technology, USA Deciphering the Dynamics of the Unconscious Brain under General Anesthesia Sten Grillner, Karolinska Institutet, Sweden Multi-Scale Modeling of Neuronal Networks - From Ion Channels to Selection of Behavior THURSDAY, MAY 26 08:30 Model Systems: Using Genetics to Deconstruct Neural Circuits Gerald M. Rubin, Janelia Research Campus, USA A Comprehensive Approach to Understanding the Fly Brain Florian Engert, Harvard University, USA
From Whole-Brain Data to Functional Circuit Models: The Zebrafish Optomotor Response
Hideyuki Okano, Keio University School of Medicine, Japan Disease Modeling and Brain Mapping Using Transgenic Marmosets 15:30 Panel 4: Evolutionary Perspectives in Understanding the Brain Chair: Sten Grillner, Karolinska Institutet, Sweden Gerald M. Rubin, Janelia Research Campus, USA Florian Engert, Harvard University, USA Hideyuki Okano, Keio University School of Medicine, Japan Hongkui Zeng, Allen Institute for Brain Science, USA 17:00 Big Data: Analyzing High-Dimensional Brain Datasets Joshua T. Vogelstein, Johns Hopkins University, USA NeuroData: Enabling Petascale Neuroscience Sean Hill, Ecole Polytechnique Fedrerale de Lausanne, Switzerland Neuroinformatics: From Big Data to Knowledge Discovery Kamil Ugurbil, University of Minnesota Medical School, USA Human Connectomics -----