[image: VVTNS.png] https://www.wwtns.online - on twitter: wwtns@TheoreticalWide You are cordially invited to the lecture given by Tim O'Leary University of Cambridge on the topic of "Flip flops and toggles for effective decision making in neural circuits*"* The lecture will be held on zoom on *April 17, 2024*, at *11:00 am EDT * To receive the zoom link: https://www.wwtns.online/register-page *Abstract: *Neural computation is inextricably bound to decisions that must be made under time pressure and uncertainty. At the level of neural circuits, single neurons need to decide whether to spike. On longer timescales, the component circuitry needs to decide whether to reconfigure to store memories and adapt to novel situations. In this talk I will focus on two fun ideas in each of these contexts by showing how nonlinearities in neural components naturally form excitable switches that enable reliable decisions to be made in fluctuating environments. I will also issue propaganda that the kind of high level, cognitive faculties that we normally associate with decision making apply equally well and are understudied at the level of neural and synaptic populations. *About VVTNS : Created as the World Wide Neuroscience Seminar (WWTNS) in November 2020 and renamed in homage to Carl van Vreeswijk in Memoriam (April 20, 2022), its aim is to be a platform to exchange ideas among theoreticians. Speakers have the occasion to talk about theoretical aspects of their work which cannot be discussed in a setting where the majority of the audience consists of experimentalists. The seminars, **held on Wednesdays at 11 am ET,** are 45-50 min long followed by a discussion. The talks are recorded with authorization of the speaker and are available to everybody on our YouTube channel.* ᐧ -- 'Life is good ..' (Carl van Vreeswijk, 1962-2022) --------------------------------------- David Hansel Directeur de Recherche au CNRS Co-Group leader Cerebral Dynamics Plasticity and Learning lab., CNRS 45 rue des Saints Pères 75270 Paris Cedex 06 Tel (Cell): +33 607508403 - ᐧ