New temporal multiple kernel learning method for characterizing relating SC to connectivity dynamics and Brain state switching
Dear all, It is my pleasure to share with you a very recent methods and data driven modelling paper from our lab on how Resting State Dynamics Meets Anatomical Structure: Temporal Multiple Kernel Learning (tMKL) Model to explore SC-dFC-FC tripartite relationship published in Neuroimage. https://www.sciencedirect.com/science/article/pii/S1053811918318597?via%3Dih... The proposed model uses spectral graph theory techniques to partitions aspects of the whole-brain dynamics essentially into two parts: (i) characterizing temporal dynamics through identification of latent transient states, and (ii) linking them to the underlying structural geometry. These two aspects are captured using a novel blend of unique methods. The proposed solution does not make strong assumptions about the underlying data and is generally applicable to resting or task data for learning subject-specific state transitions and for successfully characterizing SC-dFC-FC relationship through a unifying framework. MATLAB code for the proposed method can be downloaded from: https://github.com/SriniwasGovindaSurampudi/tMKL Any comments/questions/suggestions on the method/code are of course welcome. Regards, Dipanjan
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Dipanjan