POSTDOC POSITIONS IN MODELING/ANALYSIS FOR UNDERSTANDING SLEEP OVERVIEW. A new NIH-funded collaboration between David Prober (Caltech), Thai Truong (USC) and Geoff Goodhill (Washington University in St Louis) aims to gain new insight into the neural circuits underlying sleep, through a combination of whole-brain neural recordings in zebrafish and theoretical/computational modeling. The Goodhill lab is now looking for 2 postdocs for the modeling and computational analysis components. PROJECT DETAILS. Using novel 2-photon imaging technologies Prober and Truong will record from the entire larval zebrafish brain at single-neuron resolution continuously for long periods of time, examining neural circuit activity during normal day-night cycles and in response to genetic and pharmacological perturbations. The Goodhill lab will analyze the resulting huge datasets using a variety of sophisticated computational approaches, and use these results to build new theoretical models that reveal how neural circuits interact to govern sleep. Theoretical and experimental work will be intimitely linked. APPLICANT PROFILE. Applicants for the positions in the Goodhill lab should have a strong background in mathematics/theory/computation applied to biological problems. Experience in modeling sleep processes is desirable but not required. LAB ENVIRONMENT. The Goodhill lab is an interdisciplinary environment of students and postdocs from a diverse array of backgrounds including neuroscience, mathematics, physics and engineering, working together on understanding neural circuit computation, particularly relating to neural development. The lab both performs its own behavioral and neural imaging experiments with larval zebrafish, and collaborates on the analysis of data generated elsewhere. UNIVERSITY ENVIRONMENT. Washington University in St Louis is ranked in the top 10 institutions globally for Neuroscience and Behavior, and offers an outstanding intellectual environment for research in neuroscience. In 2023 the Goodhill lab will move along with over 100 other labs into Washington University's new start-of-the-art 600,000 sq ft Neuroscience Research Building (https://neuroscience.wustl.edu/research/neuroscience-building). For more information about St Louis see https://explorestlouis.com. To apply please send a detailed CV and cover letter explaining your interest in the positions to g.goodhill@wustl.edu. Review of applications will continue until the positions are filled. Professor Geoffrey J Goodhill Departments of Developmental Biology, Neuroscience, Biomedical Engineering, and Electrical and Systems Engineering Washington University in St Louis St Louis, MO 63110 https://neuroscience.wustl.edu/people/geoffrey-goodhill-phd Email: g.goodhill@wustl.edu