Computational Strategies in Epilepsy Modeling and Seizure Control Workshop CNS*2025 in Florence, Italy on July 08-09, 2025 We are happy to announce our Epilepsy workshop at the 34th Annual Computational Neuroscience Meeting in Florence. The event will take place on the morning of July 8th and all day of July 9th. To participate, you must be registered for at least the workshops on the organizer's website: https://www.cnsorg.org/cns-2025. For presentation abstracts and workshop schedule see: https://brady.cs.cas.cz/ocns-epilepsy-workshop. *Abstract* Epilepsy remains a complex neurological condition, necessitating innovative approaches to understanding and mitigating seizure activity. This workshop is designed to bring together computational neuroscientists and researchers with experimental and clinical background to explore cutting-edge strategies in epilepsy modeling and seizure control. For the general content structure, we plan to start from a modeler's perspective and then progressively move towards more data-driven approaches. The first session will explore seizure mechanisms through biophysical and neural mass models at different temporal and spatial scales, investigating, among others, ionic dynamics and network plasticity. It aims to understand seizure initiation, progression, and duration. The second session will focus on the application of computational models to EEG data recorded in epileptic patients. First, it will discuss the promising advances in seizure monitoring using wearable devices and long-term EEG recordings, particularly focusing on the use of data features inspired by concepts derived from mathematical modeling in epilepsy. Then, it will move on to advanced parameter inference methods to tailor models to individual data samples in order to provide mechanistic insight. The third session will examine stimulation-based strategies to terminate or prevent seizures. There will be a focus on recent advancements in closed-loop and low-frequency electrical stimulation to control seizures. On top of model-based approaches, this session will also include the clinical perspective on stimulation treatment and data-driven studies. *Our speakers are:* - *Piotr Suffczynski*, *Department of Biomedical Physics, University of Warsaw, Poland* - *Elif Köksal-Ersöz*, *Centre de Recherche en Neurosciences de Lyon - Inserm / CNRS, France* - *Louisiane Lemaire*, *MathNeuro team, University of Montpellier, France* - *Viktor Sip*, *Institut de Neurosciences des Systèmes, Aix-Marseille Université, INSERM, France* - *Brian Litt*, *Department of Neurology and Bioengineering, University of Pennsylvania, Philadelphia, USA* - *Christian Meisel*, *Department of Neurology and Berlin Institute of Health, Universitätsmedizin Berlin, Germany* - *Isa Dallmer-Zerbe*, *Institute of Computer Science of the Czech Academy of Sciences, Czech Republic* - *Dominic Dunstan*, *Department of Mathematics & Statistics, University of Exeter, Exeter, United Kingdom* - *Levin Kuhlmann*, *Department of Data Science and AI, Faculty of Information Technology, Monash University, Australia* - *Guillaume Girier*, *Institute of Computer Science of the Czech Academy of Sciences, Czech Republic* - *Matthew Szuromi*, *Boston University, USA* - *Laila Weyn*, *Department of Information Technology (INTEC), Ghent University/IMEC, Belgium* - *Daria Nesterovich Anderson**, **Faculty of Engineering, University of Sydney, Australia* We will be delighted to welcome you. GIRIER Guillaume, Postdoc Researcher, Complex networks and Brain Dynamics Group COBRA project: http://cobra.cs.cas.cz BRADY project: https://brady.cs.cas.cz/ girier@cs.cas.cz | *Personal website <https://sites.google.com/view/guillaumegirier/>*