Open Ph.D. position on whole-brain calcium imaging at Technical University of Munich
We are currently looking for a Ph.D. Student interested in functionally dissecting whole-brain calcium imaging data with cellular resolution obtained from zebrafish larvae undergoing systematic perturbations of neuronal activity. Our laboratory (westmeyerlab.org) at the School of Medicine of Technical University of Munich (https://www.tum.de/nc/en/homepage/) and The Institute for Biological and Medical Imaging (IBMI) http://www.helmholtz-muenchen.de/en/ibmi/ focuses on biological engineering of molecular sensors and actuators for neurobehavioral imaging. We have built a molecular imaging pipeline consisting of state-of-the-art fluorescent imaging techniques including neurobehavioral methods to simultaneously image behavior and brain activity in freely behaving animals (see for example NeuBtracker.org). We complement these dataset with exoeriments conducted by Light Sheet Microscopy and Light Field microscopy to obtain imaging volumes with high temporal sampling and confocal / 2-photon microscopy. We also capture calcium signaling from adult zebrafish and rodent brains using combined acquisitions with optoacoustic tomography or MRI. For our inter-disciplinary work, we are actively collaborating within Europe and in particular also with MIT and Caltech. If you are interested in computational analyses of whole-brain calcium imaging data, please visit westmeyerlab.org and submit a brief statement of your research interests and your CV to Gil Westmeyer.
Postdoctoral Position at the Max Planck Institute for Biological Cybernetics in Tübingen, Germany The Department of High-field Magnetic Resonance at the Max Plank Institute for Biological Cybernetics in Tübingen is offering TWO postdoctoral positions. This position is open now until filled.
Research Description: Understand and learn to control the brain circuits underlying critical brain states. Potential assignments:
Position #1 (Bio-engineering and computational direction) a) Build up a real-time bio-feedback controlling system for brain functional studies: i) Neural network-based signal processing, ii) MR-guided robotic system development, iii) Machine learning-based multi-modal brain signal dynamic prediction. b) High field MRI methodology development and applications i) High spatiotemporal fMRI method development from rodents to humans. ii) Advanced resting-state fMRI analysis method development based on the neural network-based learning schemes. Candidates with strong computational skills are highly encouraged to apply for this position.
Position #2 (multi-modality imaging in animal brains, Biologists/biomedical engineers/electrophysiologists) a) Implement the MRI/EEG/calcium recording methods for global brain state monitoring. b) Target specific nuclei with deep brain optogenetic stimulation methods to study circuit-specific brain state neuromodulation. c) Develop an advanced fiber-optic imaging device for MRI compatible concurrent brain dynamic signal recordings, e.g., Ca2+, Glutamate, K+, and other neuromodulators. Experience with viral transfection, 2-PM or fiber optic recordings, or in vivo. / in vitro. electrophysiology in animal models (rodents) is highly desirable. The candidates should bear experience or strong interests in brain functional imaging, e.g. task-based BOLD fMRI.
The Max Plank Institute for Biological Cybernetics is located in Tübingen, Germany. The High-field Magnetic Resonance Department is equipped with the 3T, 9.4T human MR scanner and 14.1T animal Bruker MR Scanner. Please send your CV (in English) to Dr. Yu (E-mail: xin.yu@tuebingen.mpg.de).
Best,
Xin
participants (2)
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Gil Westmeyer -
Xin Yu