The Simons Collaboration on the Global Brain (SCGB) hosts postdoc/student meetings to bring together trainees interested in neural coding and dynamics to discuss ideas and data. In addition to regional meetings in New York, Boston, and the Bay Area, SCGB holds a Global virtual series to connect systems and computational neuroscientists across the world. We would love to see you at this month's Global meeting! Please see event details and Zoom link below. SCGB Global Postdoc/Student Meeting: https://www.eventbrite.com/e/scgb-global-postdocstudent-meeting-tickets-1638... Thursday, August 5th, 1pm Eastern Time https://simonsfoundation.zoom.us/j/93637538440?pwd=MnNCeVF1eThKZmVUa2p5bUlRR... Passcode: 443599 *Kayvon Daie*Research Associate, Svoboda Laboratory HHMI's Janelia Research Campus *Dissection of the neural circuitry underlying short-term memory* Short-term memory is associated with persistent neural activity without sustained input, arising from the interactions between neurons with brief time constants. A variety of neural circuit models could account for existing measurements of neural activity. To explore which, if any, of these models are most consistent with neural circuitry, we measured coupling between functionally characterized motor cortex neurons in mice performing a memory-guided response task. Targeted two-photon photostimulation of small (<10) groups of neurons produced sparse calcium responses in coupled neurons over approximately 100 μm. Neurons with similar task-related selectivity were preferentially coupled. Photostimulation of different groups of neurons modulated activity in different subpopulations of coupled neurons. Responses of stimulated and coupled neurons persisted for seconds, far outlasting the duration of the photostimuli. Photostimuli produced behavioral biases that were predictable based on the tuning of the photostimulated population, even though photostimulation preceded the behavioral response by seconds. Our results suggest that memory-related neural circuits contain intercalated, recurrently connected modules and that these modules are coupled via long-range “hidden feedforward” connections. *Please note that this meeting is open to all neuroscience postdocs and PhD students, regardless of location or SCGB affiliation (sorry, no PIs). *After Q&A with the speaker, we will open breakout rooms for anyone interested in staying to chat, network, or further discuss the talk. In addition to these breakouts, SCGB Scientific Staff will be available for "office hours" to chat and answer questions about SCGB programs and support. Registration on EventBrite is encouraged but not required: https://www.eventbrite.com/e/scgb-global-postdocstudent-meeting-tickets-1638... Please contact Laura Long at llong@simonsfoundation.org with any questions. Sign up for our mailing list here: https://forms.gle/DZa1b2WCtvw5XFhAA