We are recruiting a Postdoctoral Researcher for an NIH-funded project investigating the neural circuit mechanisms of working memory decline in aging and Alzheimer’s disease. The postdoc will be based at Boston University in the laboratory of Dr. J. Luebke<https://www.bumc.bu.edu/anatneuro/luebke-lab-2/> in Boston, MA and work primarily on computational modeling of large-scale prefrontal cortex networks, under the remote supervision of Dr. Klaus Wimmer<https://www.crm.cat/_neuroscience/> (Centre de Recerca Matematica, Barcelona, Spain). The project combines computational and empirical approaches, and the postdoc will develop large-scale spiking network models that incorporate biologically realistic perturbations such as myelin changes, synapse loss, and neuronal hyperexcitability. The position offers close interaction with experimental collaborators, opportunities to generate testable predictions, and strong support for publishing and presenting work internationally. Qualifications * PhD in computational neuroscience, physics, computer science, applied mathematics, or a related field. * Strong programming skills (Python; experience with simulation environments like Brian2, NEST, or NEURON a plus). * Background in neural network modeling, systems neuroscience, or dynamical systems. Position Details * Initial appointment: 1 year, renewable based on performance and funding. * Start date: Flexible, ideally Fall/Winter 2025. * Salary and benefits follow NIH/BU guidelines. How to Apply Please send a CV, a short cover letter describing your research interests, and contact details for 2–3 referees to kwimmer@crm.cat<mailto:kwimmer@crm.cat>. Applications will be reviewed on a rolling basis until the position is filled. CONFIDENTIALITY AND PRIVACY NOTICE: This message and the documents that might be attached, are addressed exclusively to their(s) recipient(s) and may contain privileged or confidential information. The access to this information by people other than those designated is not authorized. If you are not the indicated recipient, you are notified that the use, disclosure and / or copying without authorization is prohibited under current legislation. If you have received this message in error, please kindly inform the sender immediately and proceed to its destruction. We inform you that the personal data contained in this document, and in particular your contact information and professional position, are protected in accordance with current legislation on the protection of personal data. Centre de Recerca Matemàtica (CRM) will process the data only for the purpose of managing the relationship you have with us. The data will be kept while the purpose for which it was collected remains. You can exercise at any time your rights to access, rectification and erasure of your personal data, as well as the right to object and restriction of processing. For this, you must contact CRM by email to dpo@crm.cat.