The Turaga Lab is looking for exceptional postdoctoral researchers and programmers (and graduate students!) for research at the intersection of machine learning and neuroscience. https://www.janelia.org/lab/turaga-lab With recent technological advances in 3d electron microscopy, optogenetics and large-scale chronic in vivo neural imaging, it is now possible to measure and perturb the activity of large populations of neurons, and to map their connectivity. These new data can be used understand how the structure of a neural circuit gives rise to its function. Our lab develops machine learning algorithms to map neural connectivity, and statistical models to characterize neural activity and to relate activity to connectivity. We have pioneered the use of deep-learning based machine learning algorithms to map neural connectivity from 3d electron microscopic images of brain tissue, and we are now working to improve these methods. This involves solving interesting new problems in structured prediction, active learning and unsupervised learning at an unprecedented scale (imagine working with labeled training datasets with 10^9 examples in a 10^6 dimensional feature space and wanting to achieve accuracies of 99.999%!). We are also developing novel statistical methods to analyze large-scale calcium imaging datasets. This is with an eye towards combining such large-scale activity measurements with structural connectomes in order to relate neural activity to neural connectivity with statistical and mechanistic models. HHMI's Janelia Research Campus is a unique, world-class research community near Washington, D.C. dedicated to understanding the function of neural circuits and developing synergistic imaging technology. Our highly collaborative structure is designed to support interdisciplinary work in small lab groups. We seek candidates who are comfortable with risk and are able to think independently to develop novel approaches. Applicants should have a strong quantitative background with degrees or expertise in machine learning, computational neuroscience, applied mathematics, physics or related discipline. Excellent collaborative programming skills in Python, C/C++, Java or similar languages are essential. To apply, please send a CV and names and addresses of 2-3 references by email to Dr. Srini Turaga, turagas@janelia.hhmi.org.