POSTDOC POSITION IN MODELING/ANALYSIS FOR UNDERSTANDING SLEEP OVERVIEW. An NIH-funded collaboration between David Prober (Caltech), Thai Truong (USC) and Geoff Goodhill (Washington University in St Louis) aims to gain new insight into the neural circuits underlying sleep, through a combination of whole-brain neural recordings in zebrafish and theoretical/computational modeling. A postdoc position is available in the Goodhill lab to contribute to the modeling and computational analysis components. PROJECT DETAILS. Using novel 2-photon imaging technologies Prober and Truong are recording from the entire larval zebrafish brain at single-neuron resolution continuously for long periods of time, examining neural circuit activity during normal day-night cycles and in response to genetic and pharmacological perturbations. The Goodhill lab is analyzing the resulting huge datasets using a variety of sophisticated computational approaches, and using these results to build new theoretical models that reveal how neural circuits interact to govern sleep. APPLICANT PROFILE. Applicants should have a strong background in mathematics/theory/computation applied to biological problems. Experience in analyzing sleep processes is desirable but not required. LAB ENVIRONMENT. The Goodhill lab is an interdisciplinary environment of students and postdocs from a diverse array of backgrounds including neuroscience, mathematics, physics and engineering, working together on understanding neural circuit computation, particularly relating to neural development. The lab both performs its own behavioral and neural imaging experiments with larval zebrafish, and collaborates on the analysis of data generated elsewhere. UNIVERSITY ENVIRONMENT. Washington University in St Louis is ranked in the top 10 institutions globally for Neuroscience and Behavior, and offers an outstanding intellectual environment for research in neuroscience. The Goodhill lab has recently moved into Washington University's new start-of-the-art 600,000 sq ft Neuroscience Research Building (https://neuroscience.wustl.edu/research/neuroscience-building). For more information about St Louis see https://explorestlouis.com. To apply please send a detailed CV and cover letter explaining your interest in the positions to g.goodhill@wustl.edu<mailto:g.goodhill@wustl.edu>. Review of applications will continue until the position is filled. Professor Geoffrey J Goodhill Departments of Developmental Biology and Neuroscience Director, Center for Theoretical and Computational Neuroscience (ctcn.wustl.edu) Affiliate appointments: Physics, Biomedical Engineering, Computer Science and Engineering, and Electrical and Systems Engineering Washington University School of Medicine 660 S. Euclid Avenue St. Louis, MO 63110 g.goodhill@wustl.edu<mailto:g.goodhill@wustl.edu> https://neuroscience.wustl.edu/people/geoffrey-goodhill-phd