The Neurobiology of Parkinson's Disease group from the Cajal Institute CSIC (Madrid) is seeking highly motivated Ph.D. candidates interested in developing a Doctoral Thesis in the field of Computational and Systems Neuroscience. The project will require the analyses of in-vivo electrophysiological, calcium imaging, and behavior recordings in mice models of Parkinson’s disease. The position requires: - MS degree in Biomedical Engineering, Bioinformatics, Computer Science, Applied Math/Physics, or equivalent. - Good communication and organizational skills are highly desirable. An English language degree is necessary. - Analytical skills required to resolve problems that entail the use of basic scientific, mathematical, and technical principles are a plus. - Experience with using MATLAB or PYTHON for signal processing is essential . - High average grades from Graduate school and master's will be highly valued. Some related publications: - Espadas I, Ortiz O, García-Sanz P, Sanz-Magro A, Alberquilla S, Solis O, Delgado-García JM, Gruart A, Moratalla R. Dopamine D2R is Required for Hippocampal-dependent Memory and Plasticity at the CA3-CA1 Synapse. Cereb Cortex. 2021 31(4):2187-2204. - García-Sanz P, M F G Aerts J, Moratalla R. The Role of Cholesterol in α-Synuclein and Lewy Body Pathology in GBA1 Parkinson's Disease. Mov Disord. 2021, 36(5):1070-1085. - Suarez LM, Solis O, Sanz-Magro A, Alberquilla S, Moratalla R. Dopamine D1 Receptors Regulate Spines in Striatal Direct-Pathway and Indirect-Pathway Neurons. Mov Disord. 2020;35(10):1810-1821. - Keifman E, Ruiz de Diego I, Pafundo DE, Paz RM, Solís O, Murer MG, Moratalla R. Optostimulation of striatonigral terminals in substantia nigra induces dyskinesia that increases after L-DOPA in a mouse model of Parkinson's disease. Br J Pharmacol. 2019;176:2146-2161. The position is funded for 2 years with an extension based on the outcome starting immediately. Interested candidates, please send the CV to Dr. Rosario Moratalla (moratalla@cajal.csic.es) until the position is fulfilled. -- Pablo Jercog, Ph.D. Team Leader Instituto Cajal Avda. Doctor Arce, 37 Madrid, Madrid, 28002, Spain cell: +34 620562808 email: pjercog@gmail.com Lab webpage <https://sites.google.com/view/pablojercogteam/>