Dear colleagues, We would like to draw your attention to our recently published book: *The Rewiring Brain: A Computational Approach to Structural Plasticity in the Adult Brain*, van Ooyen, A, and Butz-Ostendorf, M, eds, Academic Press, June 2017. For more information (preview) and to order the book, go to https://www.elsevier.com/books/the-rewiring-brain/van- ooyen/978-0-12-803784-3 Also see https://anvooyen.home.xs4all.nl/papers/TheRewiringBrain.html *Description* The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In *The Rewiring Brain*, the editors bring together, for the first time, contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and *The Rewiring Brain* shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists. Key features: · Reviews the current state of knowledge of structural plasticity in the adult brain. · Gives a comprehensive overview of computational studies on structural plasticity · Provides insights into the potential driving forces of structural plasticity and the functional implications of structural plasticity for learning and memory · Serves as inspiration for developing novel treatment strategies for stimulating functional repair after brain damage *Book Contents* Editorial *Arjen van Ooyen and Markus Butz-Ostendorf* Section I. Experimental background 1. Structural plasticity and cortical connectivity *Vassilis Kehayas and Anthony Holtmaat* 2. Structural plasticity induced by adult neurogenesis *Gregory W. Kirschen, Kurt A. Sailor, and Shaoyu Ge* 3. Structural neural plasticity during stroke recovery *Kimberly Gerrow and Craig E. Brown* 4. Is lesion-induced synaptic rewiring driven by activity homeostasis? *Markus Butz-Ostendorf and Arjen van Ooyen* Section II. Homeostatic structural plasticity 5. Network formation through activity-dependent neurite outgrowth: a review of a simple model of homeostatic structural plasticity *Arjen van Ooyen* 6. Clustered arrangement of inhibitory neurons can lead to oscillatory dynamics in a model of activity-dependent structural plasticity *Rosanna C. Barnard, Istvan Z. Kiss, Simon F. Farmer, and Luc Berthouze* 7. A detailed model of homeostatic structural plasticity based on dendritic spine and axonal bouton dynamic *s**Markus Butz-Ostendorf and Arjen van Ooyen* 8. Critical periods emerge from homeostatic structural plasticity in a full-scale model of the developing cortical column *Sebastian Rinke, Mikael Naveau, Felix Wolf and Markus Butz-Ostendorf* 9. Lesion-induced dendritic remodeling as a new mechanism of homeostatic structural plasticity in the adult brain *Steffen Platschek, Hermann Cuntz, Thomas Deller, and Peter Jedlicka* Section III. Structural plasticity and connectivity 10. The role of structural plasticity in producing nonrandom neural connectivity *Paul Miller* 11. Structural plasticity and the generation of bidirectional connectivity *Daniel Miner, Felix Z. Hoffmann, Florence Kleberg, and Jochen Triesch* 12. Spike timing-dependent structural plasticity of multicontact synaptic connections *Moritz Deger* 13. Selection of synaptic connections by wiring plasticity for robust learning by synaptic weight plasticity *Naoki Hiratani and Tomoki Fukai* Section IV. Structural plasticity and learning and memory 14. Within a spine's reach *Will DeBello and Karen Zito* 15. Impact of structural plasticity on memory capacity *Panagiotis Bozelos and Panayiota Poirazi* 16. Long-term information storage by the interaction of synaptic and structural plasticity *Michael Fauth, Florentin Wörgötter, and Christian Tetzlaff* 17. Impact of structural plasticity on memory formation and decline *Andreas Knoblauch* Section V. Neurogenesis-related structural plasticity 18. Adult neurogenesis and synaptic rewiring in the hippocampal dentate gyrus *Arjen van Ooyen, Gertraud Teuchert-Noodt, Keren Grafen, and Markus Butz-Ostendorf* 19. Modifications in network structure and excitability may drive differential activity dependent integration of granule cells into dentate gyrus circuits during normal and pathological adult neurogenesis *Quinton Skilling, James Roach, Alison L. Althaus, Geoffrey G. Murphy, Leonard Sander, and Michal Zochowski* 20. Computational perspectives on adult neurogenesis *Kristofor D. Carlson, Fredrick Rothganger, and James B. Aimone* 21. Restricted boltzmann machine models of hippocampal coding and neurogenesis *Rory Finnegan, Mark Shaw, and Suzanna Becker* Section VI. Structural plasticity and pathology 22. Modeling the impact of lesions in the brain *Sol Lim, Frances Hutchings, and Marcus Kaiser* 23. Network models of epilepsy-related pathological structural and functional alterations in the dentate gyrus *Ivan Raikov, Mark Plitt, and Ivan Soltesz* 24. Computational models of stroke recovery *Vittorio Sanguineti* 25. Neural plasticity in human brain connectivity: the effects of deep brain stimulation *Tim J. van Hartevelt, Henrique M. Fernandes, Angus B. A. Stevner, Gustavo Deco, and Morten L. Kringelbach*