A postdoctoral position is available in the lab of Prof Mark Humphries at the University of Nottingham. We seek a postdoctoral researcher to tackle the deep question of how dopamine controls the dynamics of the striatum. As the main target of dopamine in the brain, the striatum bears the brunt of dopamine loss in Parkinson’s disease. Yet how dopamine controls the output of the striatum, and how the loss of dopamine disrupts that output, is unknown. The successful candidate will be responsible for constructing and simulating models of the striatum to investigate how dopamine controls the striatum’s dynamics, and the implications this will have for Parkinson’s disease. The project will build upon the detailed models of the striatum from the Humphries group (e.g. Humphries et al 2009 Neural Networks; 2010, PLoS Computational Biology). This is also a chance to join the newly-created computational neuroscience centre at Nottingham, which includes Profs Mark van Rossum and Stephen Coombes. Find out more about the lab and its interests here: https://www.humphries-lab.org/ The post will be available for 18 months in the first instance. More details, eligibility, and application instructions here: https://www.nottingham.ac.uk/jobs/currentvacancies/ref/SCI353818 Deadline: 7th November 2018 To discuss this or other projects, please contact Mark (mark.humphries@nottingham.ac.uk).