Dear Colleagues,
we would like to draw your attention to the recently reprogrammed "Virtual
Physiology" teaching tools, including two neurophysiology
labs: SimNerv and SimNeuron. More information is given on our
website www.virtual-physiology.com
from where you also can download fully functioning demo versions for
Windows.
SimNerv offers a realistic lab environment on the
computer screen to perform classical experiments of compound action
potential recordings from the frog sciatic nerve. All parameters of
the stimulating and recording devices are freely adjustable.
Mathemathical algorithms guarantee for appropriate reactions of the
nerves, also considering their physological diversity.
SimNeuron offers easy to overlook laboratories for voltage-
and current clamp experiments on the basis of simplified
Hodgkin-Huxley type equations, described, for example, in Tchaptchet
et al., Brain Res, 1536: 159-167. A neuron editor allows altering
the neuron's parameters to examine their impact on the neurons'
dynamics.
In addition to these neurophysiology labs you also can download
fully functioning demo versions of SimMuscle and SimHeart,
featuring classical experiments with nerve-muscle preparations of
the frog and with the isolated heart of the rat in the widely used
Langendorff set-up for drug perfusion.
To ask for more information, reprints (see short list below), or
prices for fully licensed versions for teaching, please, send a
reply.
We hope you and your students will enjoy working in the virtual
physiology laboratories.
Best regards
Hans Braun and the Virtual Physiology team
References:
see also http://www.uni-marburg.de/fb20/physiologie/ags/braun/publications
or https://www.researchgate.net/profile/Hans_Braun/contributions?ev=prf_act
SimNeuron
related references:
Tchaptchet
A,
Postnova S, Finke C, Schneider H, Huber MT, Braun HA (2013):
Modelin Neuronal Activity in Relation to Experimental
Voltage-/Patch-Clamp Recordings. Brain Res 1536: 159-167, http://dx.doi.org/10.1016/j.brainres.2013.06.029
PubMed: http://www.ncbi.nlm.nih.gov/pubmed/23911648
Science direct: http://www.sciencedirect.com/science/article/pii/S0006899313009153
- or send a mail to braun@uni-marburg.de
Postnova S,
Finke C, Huber MT, Voigt K, Braun HA (2011): Conductance-Based
Models of Neurons and Synapses for the Evaluation of Brain
Functions, Disorders and Drug Effects. In: Biosimulation in
Biomedical Research, Health Care and Drug Development. Eds.:
Erik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan.
Springer, Wien - New York, pp 93 – 126. Can be downloaded from our website www.virtual-physiology
.com
General
reports on the first Virtual Physiology release:
Braun HA
(2003) Virtual versus real laboratories in life-science
education: Concepts and experiences. In: Jukes N and Chiuia M
(Eds) From guinea pig to computer mouse. Interniche, pp 81-87. Can be downloaded from our
website www.virtual-physiology
.com
Bahar S (2000)
The Real and Virtual Laboratory: A Conversation with Dr. Hans
Braun. In: The Biological Physicist, The Newsletter of the
Division of Biological Physics of the American Physical Society.
Vol.1 No.1 June 2001 p 5-7. Can
be downloaded from our website www.virtual-physiology
.com
A
recent Poster for the 2014 Conference of the German
Physiological Society:
Braun HA, Tchaptchet A,
dell Oro-Friedl J, Immer D, Schneider H, Braun T, Postnova S,
Semyachkina-Glushkovskaya O, Schwabedal J, Wenzel S, Voigt K,
Hirsch M: Learning by Doing with the Virtual Physiology
Series:Physiological and Pharmacological in silico Experiments. Can be downloaded
from our website www.virtual-physiology
.com
--
Hans A. Braun
Neurodymics Lab, Institute of Physiology,
Philipps University of Marburg
Deutschhaustr. 2, D-35037 Marburg, Germany
Phone: +49 6421 286-2305, Mobile: +49 173 319 3028,
email: braun@staff.uni-marburg.de
URL: www.uni-marburg.de/fb20/physiologie/ags/braun
see also: www.virtual-physiology.com/