Bridging the gap for mathematical models of gap junctions

PhD and post-doctoral positions available with Dr Áine Byrne (https://people.ucd.ie/aine.byrne) in the School of Mathematics and Statistics at University College Dublin’s .

This project seeks to develop novel mathematical models of gap junction modulation in the brain. Gap junctions promote the synchronous activation of neurons, a signature of epileptic seizures. Using a combination of mathematical models and electrophysiological experiments, we will investigate the interplay between gap junction coupling and neuronal synchronisation. Particular attention will be paid to how gap junction coupling varies in response to changes in the surrounding environment. This newfound understanding will be exploited to understand the emergence of excessive neuronal synchronisation in epilepsy and identify novel treatments. Experiments will be carried out at Trinity College Dublin under the guidance of collaborator Prof Mark Cunningham (https://www.cunninghamlab.org/) who will provide training and the use of his facilities.

PhD student

A 4-year fully funded position is available from September 1st, 2024. Funding includes a stipend of €22,000 per year and a travel allowance of €1,500 per year (years 2-4). Candidates should have a strong mathematical background, programming skills (Python, LaTeX, C++, Linux), an excellent command of the English language, good communication skills, and a passion for interdisciplinary projects. A MSc in mathematics, physics, computer science or a related field is desirable, but candidates with an excellent undergraduate degree (first class honours) may also apply. 

Applications, including a personal statement, CV, and contact details for two referees should be sent to Áine Byrne (aine.byrne@ucd.ie). The deadline for applications is July 15, 2024, however, later applications may also be considered.

Post-doctoral positions

We are currently accepting expressions of interest for a 3-year position (start date: January 1st, 2025). Candidates should have a PhD in applied mathematics, physics, computer science, neuroscience, cognitive science or a related field. Mathematical or computational modelling experience is required, while experimental experience is desirable (but not essential). Candidates should also have strong programming skills (Python, LaTeX, XPPAUTO, C++, Linux), an excellent command of the English language, good communication skills, and a passion for interdisciplinary projects

Expressions of interest, including a short description of your previous experience and motivation for working on this project, should be sent to Áine Byrne (aine.byrne@ucd.ie). A formal application procedure will follow in the coming months.