Nervous systems, like any evolved structure, encounter unavoidable trade-offs between multiple tasks. They must fulfil their fundamental computational functions whilst consuming as little energy as possible and remaining robust to potential environmental
changes. These tasks are often in direct opposition to one another, and a general quantification of the relative importance of individual optimisation targets is non-trivial. The problem is complicated by the degeneracy seen across neurons and circuits, where
multiple different combinations of components can lead to similar functional behaviours. Pareto optimality might provide a useful framework to analyse neurobiological systems from biophysically detailed cells to large-scale network structures that combine
high-dimensional parameter spaces with high-dimensional objective spaces. Pareto, or multi-objective, optimality can, for example, help to identify geometrically simple subspaces of neuronal models that cannot be improved upon for all relevant objectives.
This workshop aims to discuss applications of Pareto optimality to the trade-offs encountered by diverse nervous systems. The talks and discussions will also address the trade-off between functional effectiveness and energetic efficiency and the concept
of metabolically efficient information processing.
Speakers include:
Astrid Prinz, Anna Levina, Timothy
O'Leary, Marcel Oberländer, Arnd Roth, Rishikesh Narayanan, Suhita
Nadkarni, Albert Gidon, Zahid Padamsey, Wiktor Mlynarski, Dylan Festa
Full details are available at:
https://www.treestoolbox.org/CNS2023_pareto_workshop/index.html
and
Hope to see you there!
Alex Bird, Philipp Norton, Peter Jedlicka, and Susanne Schreiber
--
Prof. Dr. Peter Jedlicka
Computer-Based Modelling
in the field of 3R Animal Protection
Faculty of Medicine
Justus Liebig University Giessen
Rudolf-Buchheim-Straße 6
35392 Gießen
Phone: ++49 (0)641 9941387
Fax: ++49 (0) 641 9941359
Email: Peter.Jedlicka@informatik.med.uni-giessen.de
3R Centre of Justus Liebig University Giessen
Interdisciplinary Centre for 3Rs in Animal Research (ICAR3R)
Frankfurter Straße 104
35392 Giessen (Germany)