We are
looking for a PhD student with a strong interest in human movement sciences and
motor learning.
How is sensorimotor adaptation acquired and
forgotten?
Scientific background: Human movement control is highly
efficient at minimizing sensorimotor errors and is forced to adjust its
strategies to slow changes of a large variety of factors. The motor system is
subject to growth, aging, or muscle weakness; the external mechanical
environment may change its resistance against the movement; and the sensory system,
providing the most important information to estimate the actual and desired
state of the ensemble of body and environment, is also subject to systematic
changes. Sensorimotor adaptation is often defined as the gradual change of the
generated motor commands in response to such systematic changes, but it has
been recently recognized that sensorimotor adaptation does not only involve the
acquisition of gradual changes in stimulus-response mechanisms, but also different
types of meta-learning reflected in 1) gradual changes in the processing of
sensorimotor errors driving the adaptation (error sensitivity) and in 2)
adjustments of the stability (retention) of the acquired adaptive change.
Current project and
methods: The
current project will investigate dynamics of error sensitivity and retention across
repeated sequences of sensorimotor adaptation and deadaptation. Of special
interest is the dependence of error sensitivity and retention on error size and
consistency. Adaptation experiments will be performed in reaching movements
under distorted visual feedback of the hand and in saccadic eye movements to
targets displaced during the movement. The data acquisition and analysis is
centered on movement trajectories recorded in humans. Candidates should have a
strong interest in motor control and learning mechanisms. Skills in
mathematical analysis of dynamic systems and computer programming are desirable.
The project involves cooperation with laboratories in Toronto (CA) and Seattle
(USA).
Contact: Dr. Ing. Thomas Eggert e-mail: eggert at lrz.uni-muenchen.de
Department of Neurology, Ludwig-Maximilians University Munich, Germany
Literature:
Straube, A., Deubel, H., Ditterich, J., & Eggert, T.
(2001). Cerebellar lesions impair
rapid saccade amplitude adaptation. Neurology, 57 (11), 2105-2108.
Krüger M,
Borbely B, Eggert T, Straube A (2012) Synergistic control of joint angle
variability: influence of target shape. Hum Mov Sci 31:1071-1089 doi:
10.1016/j.humov.2011.12.002
Borbély BJ,
Straube A, Eggert T (2014) Motor synergies during manual tracking differ
between familiar and unfamiliar trajectories. Experimental Brain Research
232:889-901
Henriques,
D.Y., Filippopulos, F., Straube, A., & Eggert, T. (2014). The cerebellum is
not necessary for visually driven recalibration of hand proprioception.
Neuropsychologia, 64C, 195-204.