The Intelligent Systems Research Centre (ISRC) at Ulster University is advertising a funded PhD position for a project titled “Unlocking the Brain's Balance: Understanding Astrocyte Influence on Neural Communication Through Computer Modelling.”

 

This cutting-edge research project at Ulster University dives into one of the brain's most fascinating mechanisms: the conversation between brain cells that keeps our minds healthy and functioning. Our brains are incredibly complex networks where different types of cells work together in perfect harmony. At the centre of this research are astrocytes - star-shaped brain cells that act as the brain's supervisors. These cells manage a crucial molecule called GABA through a specialised transporter (GAT-3), which acts like a traffic controller for brain signals. When this system doesn't work properly, it can lead to various conditions that affect millions worldwide, including epilepsy, schizophrenia, and autism spectrum disorder (ASD).

 

What We'll Do

Using advanced computer modelling, this project will create detailed models of how brain cells interact, study how GABA levels affect brain circuit behaviour and investigate how changes in this system might lead to neurological conditions.

 

Throughout this PhD, you'll gain expertise in:

 

More details about this position are available at Unlocking the Brain's Balance: Understanding Astrocyte Influence on Neural Communication Through Computer Modelling

 

For more information about the research environment at ISRC, visit About Intelligent Systems Research Centre

 

The PhD position is at Ulster University's Derry campus, one of the UK's top 10 research institutions. Recently named 'University of the Year 2024' by Times Higher Education, Ulster University is now the highest-ranked higher education institution in the UK and Ireland.

The historic city of Derry, situated on the River Foyle in Northwest Northern Ireland, offers an ideal location between the Wild Atlantic Way and Causeway Coast. Its rich cultural heritage, vibrant atmosphere, and numerous family activities make it an excellent place to live.

 

Please contact Bronac (b.flanagan@ulster.ac.uk) if you are interested or have questions.

 

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