Mike X Cohen and Paul Tiesinga are searching for a PhD Candidate to work on a project entitled “Midfrontal Cortex Theta Oscillations: Causes and Consequences”. This project is funded by the European Research Council and is hosted by the Donders Centre for Neuroscience.
Theta-band oscillations (~6 Hz) in the medial prefrontal cortex are a signature of several important cognitive functions, including behaviour monitoring, action adjustments and feedback-driven learning. Although this consistent finding has emerged in several species including humans, monkeys, and rats, little is known about the microcircuits in the medial prefrontal cortex that generate theta oscillations and the role of those oscillations in the neural computations underlying cognitive control functions. In this project, we aim to gain more insight into these processes by employing biophysically-informed computational models to simulate the genesis and significance of midfrontal theta for coordinating local and long-range network dynamics. Empirical experiments in humans and rodents may be incorporated into the research in order to test/refine the models.
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